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PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.
Hou X, Kumar A, Lee C, Wang B, Arjunan P, Dong L, Maminishkis A, Tang Z, Li Y, Zhang F, Zhang SZ, Wardega P, Chakrabarty S, Liu B, Wu Z, Colosi P, Fariss RN, Lennartsson J, Nussenblatt R, Gutkind JS, Cao Y, Li X. Hou X, et al. Among authors: zhang sz, zhang f. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12216-21. doi: 10.1073/pnas.1004143107. Epub 2010 Jun 21. Proc Natl Acad Sci U S A. 2010. PMID: 20566880 Free PMC article.
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.
Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X. Tang Z, et al. Among authors: zhang sz, zhang f, zhang y. J Exp Med. 2010 Apr 12;207(4):867-80. doi: 10.1084/jem.20091704. Epub 2010 Mar 15. J Exp Med. 2010. PMID: 20231377 Free PMC article.
Proliferative and survival effects of PUMA promote angiogenesis.
Zhang F, Li Y, Tang Z, Kumar A, Lee C, Zhang L, Zhu C, Klotzsche-von Ameln A, Wang B, Gao Z, Zhang S, Langer HF, Hou X, Jensen L, Ma W, Wong W, Chavakis T, Liu Y, Cao Y, Li X. Zhang F, et al. Cell Rep. 2012 Nov 29;2(5):1272-85. doi: 10.1016/j.celrep.2012.09.023. Epub 2012 Nov 1. Cell Rep. 2012. PMID: 23122957 Free article.
687 results