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Time course characterization of serum cardiac troponins, heart fatty acid-binding protein, and morphologic findings with isoproterenol-induced myocardial injury in the rat.
Clements P, Brady S, York M, Berridge B, Mikaelian I, Nicklaus R, Gandhi M, Roman I, Stamp C, Davies D, McGill P, Williams T, Pettit S, Walker D; ILSI HESI Cardiac Troponins Working Group; Turton J. Clements P, et al. Among authors: mikaelian i. Toxicol Pathol. 2010 Aug;38(5):703-14. doi: 10.1177/0192623310374969. Epub 2010 Jun 28. Toxicol Pathol. 2010. PMID: 20585145
Serum cardiac troponin I concentrations transiently increase in rats given rosiglitazone.
Mikaelian I, Buness A, Hirkaler G, Fernandes R, Coluccio D, Geng W, Visalli T, Bachynsky MO, Berkofsky-Fessler W, Kanwal C, Hilton H, Nicklaus R, Hoflack JC, Dunn M, Sanders M, Giron M, Boyle BW, Singer T, Dick LS. Mikaelian I, et al. Toxicol Lett. 2011 Mar 5;201(2):110-5. doi: 10.1016/j.toxlet.2010.12.012. Epub 2010 Dec 21. Toxicol Lett. 2011. PMID: 21172411
Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.
Mikaelian I, Cameron M, Dalmas DA, Enerson BE, Gonzalez RJ, Guionaud S, Hoffmann PK, King NM, Lawton MP, Scicchitano MS, Smith HW, Thomas RA, Weaver JL, Zabka TS; Vascular Injury Working Group of the Predictive Safety Consortium. Mikaelian I, et al. Toxicol Pathol. 2014 Jun;42(4):635-57. doi: 10.1177/0192623314525686. Epub 2014 Apr 28. Toxicol Pathol. 2014. PMID: 24777748
Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas.
Long AJ, Sampson E, McCarthy RW, Harris CM, Barnard M, Shi D, Conlon D, Caldwell R, Honor D, Wishart N, Hoemann M, Duggan L, Fritz D, Stedman C, O'Connor E, Mikaelian I, Schwartz A. Long AJ, et al. Among authors: mikaelian i. Toxicol Pathol. 2016 Oct;44(7):998-1012. doi: 10.1177/0192623316654015. Epub 2016 Jun 19. Toxicol Pathol. 2016. PMID: 27324990
119 results