Hewitt DP - Search Results

1

Mechanism of antibody reduction in cell culture production processes.

Kao YH, Hewitt DP, Trexler-Schmidt M, Laird MW. Kao YH, et al. Among authors: hewitt dp. Biotechnol Bioeng. 2010 Nov 1;107(4):622-32. doi: 10.1002/bit.22848. Biotechnol Bioeng. 2010. PMID: 20589844

2

Rapid identification of low level glycation sites in recombinant antibodies by isotopic labeling with 13C6-reducing sugars.

Zhang J, Zhang T, Jiang L, Hewitt D, Huang Y, Kao YH, Katta V. Zhang J, et al. Anal Chem. 2012 Mar 6;84(5):2313-20. doi: 10.1021/ac202995x. Epub 2012 Feb 24. Anal Chem. 2012. PMID: 22324758

3

Identification and characterization of buried unpaired cysteines in a recombinant monoclonal IgG1 antibody.

Zhang T, Zhang J, Hewitt D, Tran B, Gao X, Qiu ZJ, Tejada M, Gazzano-Santoro H, Kao YH. Zhang T, et al. Anal Chem. 2012 Aug 21;84(16):7112-23. doi: 10.1021/ac301426h. Epub 2012 Aug 1. Anal Chem. 2012. PMID: 22794164

4

Quantitation and characterization of process impurities and extractables in protein-containing solutions using proton NMR as a general tool.

Skidmore K, Hewitt D, Kao YH. Skidmore K, et al. Biotechnol Prog. 2012 Nov-Dec;28(6):1526-33. doi: 10.1002/btpr.1620. Epub 2012 Nov 1. Biotechnol Prog. 2012. PMID: 22915490

5

Identification of a single base-pair mutation of TAA (Stop codon) → GAA (Glu) that causes light chain extension in a CHO cell derived IgG1.

Zhang T, Huang Y, Chamberlain S, Romeo T, Zhu-Shimoni J, Hewitt D, Zhu M, Katta V, Mauger B, Kao YH. Zhang T, et al. MAbs. 2012 Nov-Dec;4(6):694-700. doi: 10.4161/mabs.22232. Epub 2012 Sep 27. MAbs. 2012. PMID: 23018810 Free PMC article.

6

The effects of membrane filters used in biopharmaceutical processes on the concentration and composition of polysorbate 20.

Lei M, Sugahara J, Hewitt D, Beane D, Jayakar R, Cornell C, Skidmore K, Kao YH, Ji J. Lei M, et al. Biotechnol Prog. 2013 Nov-Dec;29(6):1503-11. doi: 10.1002/btpr.1824. Epub 2013 Oct 23. Biotechnol Prog. 2013. PMID: 24124005

7

Enzymatic basis of the Fc-selective intra-chain disulfide reduction and free thiol content variability in an antibody produced in Escherichia coli.

Baginski TK, Veeravalli K, McKenna R, Williams C, Wong K, Tsai C, Hewitt D, Mani K, Laird MW. Baginski TK, et al. Microb Cell Fact. 2022 Aug 19;21(1):167. doi: 10.1186/s12934-022-01892-4. Microb Cell Fact. 2022. PMID: 35986313 Free PMC article.

8

Quantitation of polysorbate 20 in protein solutions using mixed-mode chromatography and evaporative light scattering detection.

Hewitt D, Zhang T, Kao YH. Hewitt D, et al. J Chromatogr A. 2008 Dec 26;1215(1-2):156-60. doi: 10.1016/j.chroma.2008.11.017. Epub 2008 Nov 14. J Chromatogr A. 2008. PMID: 19036378

9

Mixed-mode and reversed-phase liquid chromatography-tandem mass spectrometry methodologies to study composition and base hydrolysis of polysorbate 20 and 80.

Hewitt D, Alvarez M, Robinson K, Ji J, Wang YJ, Kao YH, Zhang T. Hewitt D, et al. J Chromatogr A. 2011 Apr 15;1218(15):2138-45. doi: 10.1016/j.chroma.2010.09.057. Epub 2010 Sep 29. J Chromatogr A. 2011. PMID: 20950816

10

Facile quantitation of free thiols in a recombinant monoclonal antibody by reversed-phase high performance liquid chromatography with hydrophobicity-tailored thiol derivatization.

Welch L, Dong X, Hewitt D, Irwin M, McCarty L, Tsai C, Baginski T. Welch L, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:158-167. doi: 10.1016/j.jchromb.2018.05.039. Epub 2018 Jun 2. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29906677

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

16 results

Search Page

Filters