Oikawa M - Search Results

1

A series of structurally novel heterotricyclic alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor-selective antagonists.

Gill MB, Frausto S, Ikoma M, Sasaki M, Oikawa M, Sakai R, Swanson GT. Gill MB, et al. Among authors: oikawa m. Br J Pharmacol. 2010 Jul;160(6):1417-29. doi: 10.1111/j.1476-5381.2010.00784.x. Br J Pharmacol. 2010. PMID: 20590632 Free PMC article.

2

Improved synthesis and in vitro/in vivo activities of natural product-inspired, artificial glutamate analogs.

Oikawa M, Ikoma M, Sasaki M, Gill MB, Swanson GT, Shimamoto K, Sakai R. Oikawa M, et al. Bioorg Med Chem. 2010 Jun 1;18(11):3795-804. doi: 10.1016/j.bmc.2010.04.044. Epub 2010 Apr 21. Bioorg Med Chem. 2010. PMID: 20472441 Free PMC article.

3

Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.

Juknaitė L, Sugamata Y, Tokiwa K, Ishikawa Y, Takamizawa S, Eng A, Sakai R, Pickering DS, Frydenvang K, Swanson GT, Kastrup JS, Oikawa M. Juknaitė L, et al. Among authors: oikawa m. J Med Chem. 2013 Mar 28;56(6):2283-93. doi: 10.1021/jm301590z. Epub 2013 Mar 13. J Med Chem. 2013. PMID: 23432124 Free PMC article.

4

Total synthesis and biological evaluation of neodysiherbaine A and analogues.

Shoji M, Akiyama N, Tsubone K, Lash LL, Sanders JM, Swanson GT, Sakai R, Shimamoto K, Oikawa M, Sasaki M. Shoji M, et al. Among authors: oikawa m. J Org Chem. 2006 Jul 7;71(14):5208-20. doi: 10.1021/jo0605593. J Org Chem. 2006. PMID: 16808508

5

Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes.

Sasaki M, Tsubone K, Shoji M, Oikawa M, Shimamoto K, Sakai R. Sasaki M, et al. Among authors: oikawa m. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5784-7. doi: 10.1016/j.bmcl.2006.08.082. Epub 2006 Sep 1. Bioorg Med Chem Lett. 2006. PMID: 16949819

6

Regioselective Domino Metathesis of Unsymmetrical 7-Oxanorbornenes with Electron-Rich Vinyl Acetate toward Biologically Active Glutamate Analogues.

Oikawa M, Ikoma M, Sasaki M, Gill MB, Swanson GT, Shimamoto K, Sakai R. Oikawa M, et al. European J Org Chem. 2009 Nov 1;2009(32):5531-5548. doi: 10.1002/ejoc.200900580. European J Org Chem. 2009. PMID: 20485531 Free PMC article.

7

Structure-activity relationships of IKM-159: Diverted synthesis and biological evaluation of a series of C5-oxy analogs.

Chiba M, Fujimoto C, Sakai R, Oikawa M. Chiba M, et al. Among authors: oikawa m. Bioorg Med Chem Lett. 2015 May 1;25(9):1869-71. doi: 10.1016/j.bmcl.2015.03.037. Epub 2015 Mar 23. Bioorg Med Chem Lett. 2015. PMID: 25862201

8

Three-Component, Diastereoselective Prins-Ritter Reaction for cis-Fused 4-Amidotetrahydropyrans toward a Precursor for Possible Neuronal Receptor Ligands.

Chiba M, Ishikawa Y, Sakai R, Oikawa M. Chiba M, et al. Among authors: oikawa m. ACS Comb Sci. 2016 Jul 11;18(7):399-404. doi: 10.1021/acscombsci.6b00046. Epub 2016 May 17. ACS Comb Sci. 2016. PMID: 27163384

9

Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships.

Sasaki M, Tsubone K, Aoki K, Akiyama N, Shoji M, Oikawa M, Sakai R, Shimamoto K. Sasaki M, et al. Among authors: oikawa m. J Org Chem. 2008 Jan 4;73(1):264-73. doi: 10.1021/jo702116c. Epub 2007 Dec 6. J Org Chem. 2008. PMID: 18052390

10

Regioselective Domino Metathesis of 7-Oxanorbornenes and Its Application to the Synthesis of Biologically Active Glutamate Analogues.

Ikoma M, Oikawa M, Gill MB, Swanson GT, Sakai R, Shimamoto K, Sasaki M. Ikoma M, et al. Among authors: oikawa m. European J Org Chem. 2008 Nov;2008(31):5215-5220. doi: 10.1002/ejoc.200800704. European J Org Chem. 2008. PMID: 19644565 Free PMC article.

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