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Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes.
Beggah AT, Escoubet B, Puttini S, Cailmail S, Delage V, Ouvrard-Pascaud A, Bocchi B, Peuchmaur M, Delcayre C, Farman N, Jaisser F. Beggah AT, et al. Among authors: farman n. Proc Natl Acad Sci U S A. 2002 May 14;99(10):7160-5. doi: 10.1073/pnas.102673599. Epub 2002 May 7. Proc Natl Acad Sci U S A. 2002. PMID: 11997477 Free PMC article.
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias.
Ouvrard-Pascaud A, Sainte-Marie Y, Bénitah JP, Perrier R, Soukaseum C, Nguyen Dinh Cat A, Royer A, Le Quang K, Charpentier F, Demolombe S, Mechta-Grigoriou F, Beggah AT, Maison-Blanche P, Oblin ME, Delcayre C, Fishman GI, Farman N, Escoubet B, Jaisser F. Ouvrard-Pascaud A, et al. Among authors: farman n. Circulation. 2005 Jun 14;111(23):3025-33. doi: 10.1161/CIRCULATIONAHA.104.503706. Epub 2005 Jun 6. Circulation. 2005. PMID: 15939817 Free PMC article.
Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.
Sainte Marie Y, Toulon A, Paus R, Maubec E, Cherfa A, Grossin M, Descamps V, Clemessy M, Gasc JM, Peuchmaur M, Glick A, Farman N, Jaisser F. Sainte Marie Y, et al. Among authors: farman n. Am J Pathol. 2007 Sep;171(3):846-60. doi: 10.2353/ajpath.2007.060991. Epub 2007 Aug 3. Am J Pathol. 2007. PMID: 17675581 Free PMC article.
154 results