Powell E - Search Results

1

Identification and characterization of a novel estrogenic ligand actinopolymorphol A.

Powell E, Huang SX, Xu Y, Rajski SR, Wang Y, Peters N, Guo S, Xu HE, Hoffmann FM, Shen B, Xu W. Powell E, et al. Biochem Pharmacol. 2010 Oct 15;80(8):1221-9. doi: 10.1016/j.bcp.2010.06.030. Epub 2010 Jun 25. Biochem Pharmacol. 2010. PMID: 20599778 Free PMC article.

2

Intermolecular interactions identify ligand-selective activity of estrogen receptor alpha/beta dimers.

Powell E, Xu W. Powell E, et al. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):19012-7. doi: 10.1073/pnas.0807274105. Epub 2008 Nov 20. Proc Natl Acad Sci U S A. 2008. PMID: 19022902 Free PMC article.

3

Discovery and total synthesis of a new estrogen receptor heterodimerizing actinopolymorphol A from Actinopolymorpha rutilus.

Huang SX, Powell E, Rajski SR, Zhao LX, Jiang CL, Duan Y, Xu W, Shen B. Huang SX, et al. Among authors: powell e. Org Lett. 2010 Aug 6;12(15):3525-7. doi: 10.1021/ol1013526. Org Lett. 2010. PMID: 20593804 Free PMC article.

4

Differential requirements of Hsp90 and DNA for the formation of estrogen receptor homodimers and heterodimers.

Powell E, Wang Y, Shapiro DJ, Xu W. Powell E, et al. J Biol Chem. 2010 May 21;285(21):16125-34. doi: 10.1074/jbc.M110.104356. Epub 2010 Mar 30. J Biol Chem. 2010. PMID: 20353944 Free PMC article.

5

Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ.

Powell E, Shanle E, Brinkman A, Li J, Keles S, Wisinski KB, Huang W, Xu W. Powell E, et al. PLoS One. 2012;7(2):e30993. doi: 10.1371/journal.pone.0030993. Epub 2012 Feb 7. PLoS One. 2012. PMID: 22347418 Free PMC article.

6

Monitoring Ligand-Activated Protein-Protein Interactions Using Bioluminescent Resonance Energy Transfer (BRET) Assay.

Coriano C, Powell E, Xu W. Coriano C, et al. Among authors: powell e. Methods Mol Biol. 2016;1473:3-15. doi: 10.1007/978-1-4939-6346-1_1. Methods Mol Biol. 2016. PMID: 27518618 Review.

7

Nuclear Receptor Cofactors in PPARgamma-Mediated Adipogenesis and Adipocyte Energy Metabolism.

Powell E, Kuhn P, Xu W. Powell E, et al. PPAR Res. 2007;2007:53843. doi: 10.1155/2007/53843. PPAR Res. 2007. PMID: 17389765 Free PMC article.

8

A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis.

Powell E, Shao J, Picon HM, Bristow C, Ge Z, Peoples M, Robinson F, Jeter-Jones SL, Schlosberg C, Grzeskowiak CL, Yang F, Wu Y, Wistuba I, Moulder SL, Symmans WF, Scott KL, Edwards JR, Liang H, Heffernan TP, Piwnica-Worms H. Powell E, et al. NPJ Breast Cancer. 2018 Apr 30;4:9. doi: 10.1038/s41523-018-0062-x. eCollection 2018. NPJ Breast Cancer. 2018. PMID: 29736411 Free PMC article.

9

The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing.

Hu X, Harvey SE, Zheng R, Lyu J, Grzeskowiak CL, Powell E, Piwnica-Worms H, Scott KL, Cheng C. Hu X, et al. Among authors: powell e. Nat Commun. 2020 Jan 24;11(1):486. doi: 10.1038/s41467-020-14304-1. Nat Commun. 2020. PMID: 31980632 Free PMC article.

10

BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation.

Li AG, Murphy EC, Culhane AC, Powell E, Wang H, Bronson RT, Von T, Giobbie-Hurder A, Gelman RS, Briggs KJ, Piwnica-Worms H, Zhao JJ, Kung AL, Kaelin WG Jr, Livingston DM. Li AG, et al. Among authors: powell e. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9600-E9609. doi: 10.1073/pnas.1807112115. Epub 2018 Sep 25. Proc Natl Acad Sci U S A. 2018. PMID: 30254159 Free PMC article.

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