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Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells.
Klopp AH, Lacerda L, Gupta A, Debeb BG, Solley T, Li L, Spaeth E, Xu W, Zhang X, Lewis MT, Reuben JM, Krishnamurthy S, Ferrari M, Gaspar R, Buchholz TA, Cristofanilli M, Marini F, Andreeff M, Woodward WA. Klopp AH, et al. Among authors: xu w. PLoS One. 2010 Aug 16;5(8):e12180. doi: 10.1371/journal.pone.0012180. PLoS One. 2010. PMID: 20808935 Free PMC article.
The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer.
Xu W, Lacerda L, Debeb BG, Atkinson RL, Solley TN, Li L, Orton D, McMurray JS, Hang BI, Lee E, Klopp AH, Ueno NT, Reuben JM, Krishnamurthy S, Woodward WA. Xu W, et al. PLoS One. 2013 Aug 27;8(8):e71508. doi: 10.1371/journal.pone.0071508. eCollection 2013. PLoS One. 2013. PMID: 24013655 Free PMC article.
Simvastatin radiosensitizes differentiated and stem-like breast cancer cell lines and is associated with improved local control in inflammatory breast cancer patients treated with postmastectomy radiation.
Lacerda L, Reddy JP, Liu D, Larson R, Li L, Masuda H, Brewer T, Debeb BG, Xu W, Hortobágyi GN, Buchholz TA, Ueno NT, Woodward WA. Lacerda L, et al. Among authors: xu w. Stem Cells Transl Med. 2014 Jul;3(7):849-56. doi: 10.5966/sctm.2013-0204. Epub 2014 May 15. Stem Cells Transl Med. 2014. PMID: 24833589 Free PMC article.
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