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Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
Fernandes MS, Reddy MM, Croteau NJ, Walz C, Weisbach H, Podar K, Band H, Carroll M, Reiter A, Larson RA, Salgia R, Griffin JD, Sattler M. Fernandes MS, et al. Among authors: reddy mm. J Biol Chem. 2010 Oct 15;285(42):32596-605. doi: 10.1074/jbc.M110.106161. Epub 2010 Jul 9. J Biol Chem. 2010. PMID: 20622007 Free PMC article.
The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.
Wernig G, Gonneville JR, Crowley BJ, Rodrigues MS, Reddy MM, Hudon HE, Walz C, Reiter A, Podar K, Royer Y, Constantinescu SN, Tomasson MH, Griffin JD, Gilliland DG, Sattler M. Wernig G, et al. Among authors: reddy mm. Blood. 2008 Apr 1;111(7):3751-9. doi: 10.1182/blood-2007-07-102186. Epub 2008 Jan 23. Blood. 2008. PMID: 18216297 Free PMC article.
Targeting JAK2 in the therapy of myeloproliferative neoplasms.
Reddy MM, Deshpande A, Sattler M. Reddy MM, et al. Expert Opin Ther Targets. 2012 Mar;16(3):313-24. doi: 10.1517/14728222.2012.662956. Epub 2012 Feb 17. Expert Opin Ther Targets. 2012. PMID: 22339244 Free PMC article. Review.
Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells.
Bhanot H, Reddy MM, Nonami A, Weisberg EL, Bonal D, Kirschmeier PT, Salgia S, Podar K, Galinsky I, Chowdary TK, Neuberg D, Tonon G, Stone RM, Asara J, Griffin JD, Sattler M. Bhanot H, et al. Among authors: reddy mm. Leukemia. 2015 Jul;29(7):1555-1563. doi: 10.1038/leu.2015.46. Epub 2015 Feb 23. Leukemia. 2015. PMID: 25703587 Free PMC article.
281 results