Rosenberg SA - Search Results

1

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells.

Kochenderfer JN, Yu Z, Frasheri D, Restifo NP, Rosenberg SA. Kochenderfer JN, et al. Among authors: rosenberg sa. Blood. 2010 Nov 11;116(19):3875-86. doi: 10.1182/blood-2010-01-265041. Epub 2010 Jul 14. Blood. 2010. PMID: 20631379 Free PMC article.

2

CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent.

Gattinoni L, Ranganathan A, Surman DR, Palmer DC, Antony PA, Theoret MR, Heimann DM, Rosenberg SA, Restifo NP. Gattinoni L, et al. Among authors: rosenberg sa. Blood. 2006 Dec 1;108(12):3818-23. doi: 10.1182/blood-2006-07-034066. Epub 2006 Aug 1. Blood. 2006. PMID: 16882704 Free PMC article.

3

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy.

Hinrichs CS, Spolski R, Paulos CM, Gattinoni L, Kerstann KW, Palmer DC, Klebanoff CA, Rosenberg SA, Leonard WJ, Restifo NP. Hinrichs CS, et al. Among authors: rosenberg sa. Blood. 2008 Jun 1;111(11):5326-33. doi: 10.1182/blood-2007-09-113050. Epub 2008 Feb 14. Blood. 2008. PMID: 18276844 Free PMC article.

4

Adoptive cell transfer: a clinical path to effective cancer immunotherapy.

Rosenberg SA, Restifo NP, Yang JC, Morgan RA, Dudley ME. Rosenberg SA, et al. Nat Rev Cancer. 2008 Apr;8(4):299-308. doi: 10.1038/nrc2355. Nat Rev Cancer. 2008. PMID: 18354418 Free PMC article. Review.

5

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers.

Boni A, Muranski P, Cassard L, Wrzesinski C, Paulos CM, Palmer DC, Gattinoni L, Hinrichs CS, Chan CC, Rosenberg SA, Restifo NP. Boni A, et al. Among authors: rosenberg sa. Blood. 2008 Dec 1;112(12):4746-54. doi: 10.1182/blood-2008-07-169797. Epub 2008 Sep 17. Blood. 2008. PMID: 18799724 Free PMC article.

6

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.

Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, Kammula US, Royal RE, Sherry RM, Wunderlich JR, Lee CC, Restifo NP, Schwarz SL, Cogdill AP, Bishop RJ, Kim H, Brewer CC, Rudy SF, VanWaes C, Davis JL, Mathur A, Ripley RT, Nathan DA, Laurencot CM, Rosenberg SA. Johnson LA, et al. Among authors: rosenberg sa. Blood. 2009 Jul 16;114(3):535-46. doi: 10.1182/blood-2009-03-211714. Epub 2009 May 18. Blood. 2009. PMID: 19451549 Free PMC article. Clinical Trial.

7

Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor.

Kochenderfer JN, Feldman SA, Zhao Y, Xu H, Black MA, Morgan RA, Wilson WH, Rosenberg SA. Kochenderfer JN, et al. Among authors: rosenberg sa. J Immunother. 2009 Sep;32(7):689-702. doi: 10.1097/CJI.0b013e3181ac6138. J Immunother. 2009. PMID: 19561539 Free PMC article.

8

A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity.

Zhao Y, Wang QJ, Yang S, Kochenderfer JN, Zheng Z, Zhong X, Sadelain M, Eshhar Z, Rosenberg SA, Morgan RA. Zhao Y, et al. Among authors: rosenberg sa. J Immunol. 2009 Nov 1;183(9):5563-74. doi: 10.4049/jimmunol.0900447. J Immunol. 2009. PMID: 19843940 Free PMC article.

9

Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.

Frankel TL, Burns WR, Peng PD, Yu Z, Chinnasamy D, Wargo JA, Zheng Z, Restifo NP, Rosenberg SA, Morgan RA. Frankel TL, et al. Among authors: rosenberg sa. J Immunol. 2010 Jun 1;184(11):5988-98. doi: 10.4049/jimmunol.1000189. Epub 2010 Apr 28. J Immunol. 2010. PMID: 20427771 Free PMC article.

10

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19.

Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler-Stevenson M, Feldman SA, Maric I, Raffeld M, Nathan DA, Lanier BJ, Morgan RA, Rosenberg SA. Kochenderfer JN, et al. Among authors: rosenberg sa. Blood. 2010 Nov 18;116(20):4099-102. doi: 10.1182/blood-2010-04-281931. Epub 2010 Jul 28. Blood. 2010. PMID: 20668228 Free PMC article. Clinical Trial.

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