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Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures.
Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parège C, Chiavarina B, Grimaldi M, Le Mével S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianférani S, Fini JB, Balaguer P, Bourguet W. Delfosse V, et al. Among authors: gruszczyk j. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2020551118. doi: 10.1073/pnas.2020551118. Proc Natl Acad Sci U S A. 2021. PMID: 33361153 Free PMC article.
Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement.
Gruszczyk J, Lim NT, Arnott A, He WQ, Nguitragool W, Roobsoong W, Mok YF, Murphy JM, Smith KR, Lee S, Bahlo M, Mueller I, Barry AE, Tham WH. Gruszczyk J, et al. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E191-200. doi: 10.1073/pnas.1516512113. Epub 2015 Dec 29. Proc Natl Acad Sci U S A. 2016. PMID: 26715754 Free PMC article.
Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites.
Loy DE, Plenderleith LJ, Sundararaman SA, Liu W, Gruszczyk J, Chen YJ, Trimboli S, Learn GH, MacLean OA, Morgan ALK, Li Y, Avitto AN, Giles J, Calvignac-Spencer S, Sachse A, Leendertz FH, Speede S, Ayouba A, Peeters M, Rayner JC, Tham WH, Sharp PM, Hahn BH. Loy DE, et al. Among authors: gruszczyk j. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8450-E8459. doi: 10.1073/pnas.1810053115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127015 Free PMC article.
Asymptomatic Plasmodium vivax infections induce robust IgG responses to multiple blood-stage proteins in a low-transmission region of western Thailand.
Longley RJ, França CT, White MT, Kumpitak C, Sa-Angchai P, Gruszczyk J, Hostetler JB, Yadava A, King CL, Fairhurst RM, Rayner JC, Tham WH, Nguitragool W, Sattabongkot J, Mueller I. Longley RJ, et al. Among authors: gruszczyk j. Malar J. 2017 Apr 28;16(1):178. doi: 10.1186/s12936-017-1826-8. Malar J. 2017. PMID: 28454546 Free PMC article.
Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development.
França CT, White MT, He WQ, Hostetler JB, Brewster J, Frato G, Malhotra I, Gruszczyk J, Huon C, Lin E, Kiniboro B, Yadava A, Siba P, Galinski MR, Healer J, Chitnis C, Cowman AF, Takashima E, Tsuboi T, Tham WH, Fairhurst RM, Rayner JC, King CL, Mueller I. França CT, et al. Among authors: gruszczyk j. Elife. 2017 Sep 26;6:e28673. doi: 10.7554/eLife.28673. Elife. 2017. PMID: 28949293 Free PMC article.
19 results