Dejongh J - Search Results

1

An Integrated Approach to the Prediction of Systemic Toxicity using Computer-based Biokinetic Models and Biological In vitro Test Methods: Overview of a Prevalidation Study Based on the ECITTS Project.

Dejongh J, Forsby A, Houston JB, Beckman M, Combes R, Blaauboer BJ. Dejongh J, et al. Toxicol In Vitro. 1999 Aug-Oct;13(4-5):549-54. doi: 10.1016/s0887-2333(99)00030-2. Toxicol In Vitro. 1999. PMID: 20654514

2

Simulation of lindane kinetics in rats.

DeJongh J, Blaauboer BJ. DeJongh J, et al. Toxicology. 1997 Sep 26;122(1-2):1-9. doi: 10.1016/s0300-483x(97)00070-x. Toxicology. 1997. PMID: 9274797

3

Computer-aided biokinetic modelling combined with in vitro data.

Van Ommen B, De Jongh J, Van De Sandt J, Blaauboer B, Hissink E, Bogaards J, Van Bladeren P. Van Ommen B, et al. Toxicol In Vitro. 1995 Aug;9(4):537-42. doi: 10.1016/0887-2333(95)00046-b. Toxicol In Vitro. 1995. PMID: 20650125

4

Evaluation of In Vitro-based simulations of toluene uptake and metabolism in rats.

Dejongh J, Blaauboer BJ. Dejongh J, et al. Toxicol In Vitro. 1997 Oct;11(5):485-9. doi: 10.1016/s0887-2333(97)00079-9. Toxicol In Vitro. 1997. PMID: 20654339

5

Simulation of toluene kinetics in the rat by a physiologically based pharmacokinetic model with application of biotransformation parameters derived independently in vitro and in vivo.

DeJongh J, Blaauboer BJ. DeJongh J, et al. Fundam Appl Toxicol. 1996 Aug;32(2):260-8. doi: 10.1006/faat.1996.0129. Fundam Appl Toxicol. 1996. PMID: 8921329

6

Estimation of systemic toxicity of acrylamide by integration of in vitro toxicity data with kinetic simulations.

DeJongh J, Nordin-Andersson M, Ploeger BA, Forsby A. DeJongh J, et al. Toxicol Appl Pharmacol. 1999 Aug 1;158(3):261-8. doi: 10.1006/taap.1999.8670. Toxicol Appl Pharmacol. 1999. PMID: 10438659

7

Neurite degeneration in differentiated human neuroblastoma cells.

Nordin-Andersson M, Forsby A, Heldring N, Dejongh J, Kjellstrand P, Walum E. Nordin-Andersson M, et al. Among authors: dejongh j. Toxicol In Vitro. 1998 Oct;12(5):557-60. doi: 10.1016/s0887-2333(98)00035-6. Toxicol In Vitro. 1998. PMID: 20654440

8

A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans.

DeJongh J, Verhaar HJ, Hermens JL. DeJongh J, et al. Arch Toxicol. 1997;72(1):17-25. doi: 10.1007/s002040050463. Arch Toxicol. 1997. PMID: 9458186

9

Absence of interactions on hepatic retention and 7-ethoxyresorufin-O-deethylation activity after co-administration of 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 2,4,5,2',4',5'-hexachlorobiphenyl.

De Jongh J, Wondergem F, Seinen W, Van den Berg M. De Jongh J, et al. Toxicology. 1992 Oct;75(1):21-8. doi: 10.1016/0300-483x(92)90122-u. Toxicology. 1992. PMID: 1455422

10

Physiologically based pharmacokinetic modeling of glycyrrhizic acid, a compound subject to presystemic metabolism and enterohepatic cycling.

Ploeger BA, Meulenbelt J, DeJongh J. Ploeger BA, et al. Among authors: dejongh j. Toxicol Appl Pharmacol. 2000 Feb 1;162(3):177-88. doi: 10.1006/taap.1999.8843. Toxicol Appl Pharmacol. 2000. PMID: 10652246

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