Tsai SC - Search Results

1

X-ray crystallographic structure of an artificial beta-sheet dimer.

Khakshoor O, Lin AJ, Korman TP, Sawaya MR, Tsai SC, Eisenberg D, Nowick JS. Khakshoor O, et al. Among authors: tsai sc. J Am Chem Soc. 2010 Aug 25;132(33):11622-8. doi: 10.1021/ja103438w. J Am Chem Soc. 2010. PMID: 20669960 Free PMC article.

2

Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase.

Korman TP, Tan YH, Wong J, Luo R, Tsai SC. Korman TP, et al. Among authors: tsai sc. Biochemistry. 2008 Feb 19;47(7):1837-47. doi: 10.1021/bi7016427. Epub 2008 Jan 19. Biochemistry. 2008. PMID: 18205400 Free PMC article.

3

Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity.

Korman TP, Hill JA, Vu TN, Tsai SC. Korman TP, et al. Among authors: tsai sc. Biochemistry. 2004 Nov 23;43(46):14529-38. doi: 10.1021/bi048133a. Biochemistry. 2004. PMID: 15544323 Free PMC article.

4

Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides.

Ames BD, Korman TP, Zhang W, Smith P, Vu T, Tang Y, Tsai SC. Ames BD, et al. Among authors: tsai sc. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5349-54. doi: 10.1073/pnas.0709223105. Epub 2008 Apr 3. Proc Natl Acad Sci U S A. 2008. PMID: 18388203 Free PMC article.

5

Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis.

Korman TP, Crawford JM, Labonte JW, Newman AG, Wong J, Townsend CA, Tsai SC. Korman TP, et al. Among authors: tsai sc. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6246-51. doi: 10.1073/pnas.0913531107. Epub 2010 Mar 23. Proc Natl Acad Sci U S A. 2010. PMID: 20332208 Free PMC article.

6

Structural and biochemical analyses of regio- and stereospecificities observed in a type II polyketide ketoreductase.

Javidpour P, Korman TP, Shakya G, Tsai SC. Javidpour P, et al. Among authors: tsai sc. Biochemistry. 2011 May 31;50(21):4638-49. doi: 10.1021/bi200335f. Epub 2011 May 4. Biochemistry. 2011. PMID: 21506596 Free PMC article.

7

Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization.

Crawford JM, Korman TP, Labonte JW, Vagstad AL, Hill EA, Kamari-Bidkorpeh O, Tsai SC, Townsend CA. Crawford JM, et al. Among authors: tsai sc. Nature. 2009 Oct 22;461(7267):1139-43. doi: 10.1038/nature08475. Nature. 2009. PMID: 19847268 Free PMC article.

8

The determinants of activity and specificity in actinorhodin type II polyketide ketoreductase.

Javidpour P, Bruegger J, Srithahan S, Korman TP, Crump MP, Crosby J, Burkart MD, Tsai SC. Javidpour P, et al. Among authors: tsai sc. Chem Biol. 2013 Oct 24;20(10):1225-34. doi: 10.1016/j.chembiol.2013.07.016. Epub 2013 Sep 12. Chem Biol. 2013. PMID: 24035284 Free PMC article.

9

Modeling linear and cyclic PKS intermediates through atom replacement.

Shakya G, Rivera H Jr, Lee DJ, Jaremko MJ, La Clair JJ, Fox DT, Haushalter RW, Schaub AJ, Bruegger J, Barajas JF, White AR, Kaur P, Gwozdziowski ER, Wong F, Tsai SC, Burkart MD. Shakya G, et al. Among authors: tsai sc. J Am Chem Soc. 2014 Dec 3;136(48):16792-9. doi: 10.1021/ja5064857. Epub 2014 Nov 19. J Am Chem Soc. 2014. PMID: 25406716 Free PMC article.

10

2.6 A X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase.

Smith P, Zhou B, Ho N, Yuan YC, Su L, Tsai SC, Yen Y. Smith P, et al. Among authors: tsai sc. Biochemistry. 2009 Nov 24;48(46):11134-41. doi: 10.1021/bi9001425. Biochemistry. 2009. PMID: 19728742 Free PMC article.

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