Freeman GJ - Search Results

1

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R. Jin HT, et al. Among authors: freeman gj. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14733-8. doi: 10.1073/pnas.1009731107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679213 Free PMC article.

2

Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness.

Harlan DM, Hengartner H, Huang ML, Kang YH, Abe R, Moreadith RW, Pircher H, Gray GS, Ohashi PS, Freeman GJ, et al. Harlan DM, et al. Among authors: freeman gj. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3137-41. doi: 10.1073/pnas.91.8.3137. Proc Natl Acad Sci U S A. 1994. PMID: 7512724 Free PMC article.

3

B7-2 expressed on EL4 lymphoma suppresses antitumor immunity by an interleukin 4-dependent mechanism.

Stremmel C, Greenfield EA, Howard E, Freeman GJ, Kuchroo VK. Stremmel C, et al. Among authors: freeman gj. J Exp Med. 1999 Mar 15;189(6):919-30. doi: 10.1084/jem.189.6.919. J Exp Med. 1999. PMID: 10075975 Free PMC article.

4

Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands.

Murtaza A, Kuchroo VK, Freeman GJ. Murtaza A, et al. Among authors: freeman gj. Int Immunol. 1999 Mar;11(3):407-16. doi: 10.1093/intimm/11.3.407. Int Immunol. 1999. PMID: 10221652

5

Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.

McAdam AJ, Chang TT, Lumelsky AE, Greenfield EA, Boussiotis VA, Duke-Cohan JS, Chernova T, Malenkovich N, Jabs C, Kuchroo VK, Ling V, Collins M, Sharpe AH, Freeman GJ. McAdam AJ, et al. Among authors: freeman gj. J Immunol. 2000 Nov 1;165(9):5035-40. doi: 10.4049/jimmunol.165.9.5035. J Immunol. 2000. PMID: 11046032

6

Intercellular adhesion molecule 1 is critical for activation of CD28-deficient T cells.

Gaglia JL, Greenfield EA, Mattoo A, Sharpe AH, Freeman GJ, Kuchroo VK. Gaglia JL, et al. Among authors: freeman gj. J Immunol. 2000 Dec 1;165(11):6091-8. doi: 10.4049/jimmunol.165.11.6091. J Immunol. 2000. PMID: 11086041

7

Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family.

McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, Freeman GJ, Umetsu DT, DeKruyff RH. McIntire JJ, et al. Among authors: freeman gj. Nat Immunol. 2001 Dec;2(12):1109-16. doi: 10.1038/ni739. Nat Immunol. 2001. PMID: 11725301

8

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.

Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Monney L, et al. Among authors: freeman gj. Nature. 2002 Jan 31;415(6871):536-41. doi: 10.1038/415536a. Nature. 2002. PMID: 11823861

9

Characterization of endogenous Chinese hamster ovary cell surface molecules that mediate T cell costimulation.

Gaglia JL, Mattoo A, Greenfield EA, Freeman GJ, Kuchroo VK. Gaglia JL, et al. Among authors: freeman gj. Cell Immunol. 2001 Nov 1;213(2):83-93. doi: 10.1006/cimm.2001.1867. Cell Immunol. 2001. PMID: 11831870

10

Protect the killer: CTLs need defenses against the tumor.

Freeman GJ, Sharpe AH, Kuchroo VK. Freeman GJ, et al. Nat Med. 2002 Aug;8(8):787-9. doi: 10.1038/nm0802-787. Nat Med. 2002. PMID: 12152031 No abstract available.

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