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Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.
Söllü C, Pars K, Cornu TI, Thibodeau-Beganny S, Maeder ML, Joung JK, Heilbronn R, Cathomen T. Söllü C, et al. Nucleic Acids Res. 2010 Dec;38(22):8269-76. doi: 10.1093/nar/gkq720. Epub 2010 Aug 16. Nucleic Acids Res. 2010. PMID: 20716517 Free PMC article.
Adding fingers to an engineered zinc finger nuclease can reduce activity.
Shimizu Y, Şöllü C, Meckler JF, Adriaenssens A, Zykovich A, Cathomen T, Segal DJ. Shimizu Y, et al. Among authors: sollu c. Biochemistry. 2011 Jun 7;50(22):5033-41. doi: 10.1021/bi200393g. Epub 2011 May 11. Biochemistry. 2011. PMID: 21528840 Free PMC article.