Schubert-Zsilavecz M - Search Results

1

Dimethylcelecoxib inhibits mPGES-1 promoter activity by influencing EGR1 and NF-κB.

Deckmann K, Rörsch F, Steri R, Schubert-Zsilavecz M, Geisslinger G, Grösch S. Deckmann K, et al. Biochem Pharmacol. 2010 Nov 1;80(9):1365-72. doi: 10.1016/j.bcp.2010.07.032. Epub 2010 Aug 3. Biochem Pharmacol. 2010. PMID: 20688046 Free article.

2

Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).

Rörsch F, Buscató E, Deckmann K, Schneider G, Schubert-Zsilavecz M, Geisslinger G, Proschak E, Grösch S. Rörsch F, et al. J Med Chem. 2012 Apr 26;55(8):3792-803. doi: 10.1021/jm201687d. Epub 2012 Apr 11. J Med Chem. 2012. PMID: 22449023

3

Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.

Hanke T, Rörsch F, Thieme TM, Ferreiros N, Schneider G, Geisslinger G, Proschak E, Grösch S, Schubert-Zsilavecz M. Hanke T, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7874-83. doi: 10.1016/j.bmc.2013.10.006. Epub 2013 Oct 16. Bioorg Med Chem. 2013. PMID: 24183739

4

Nonacidic inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1) identified by a multistep virtual screening protocol.

Rörsch F, Wobst I, Zettl H, Schubert-Zsilavecz M, Grösch S, Geisslinger G, Schneider G, Proschak E. Rörsch F, et al. J Med Chem. 2010 Jan 28;53(2):911-5. doi: 10.1021/jm9012505. J Med Chem. 2010. PMID: 20025212

5

Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity.

Steri R, Achenbach J, Steinhilber D, Schubert-Zsilavecz M, Proschak E. Steri R, et al. Biochem Pharmacol. 2012 Jun 15;83(12):1674-81. doi: 10.1016/j.bcp.2012.02.027. Epub 2012 Mar 7. Biochem Pharmacol. 2012. PMID: 22414727

6

A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.

Revermann M, Mieth A, Popescu L, Paulke A, Wurglics M, Pellowska M, Fischer AS, Steri R, Maier TJ, Schermuly RT, Geisslinger G, Schubert-Zsilavecz M, Brandes RP, Steinhilber D. Revermann M, et al. Br J Pharmacol. 2011 Aug;163(8):1721-32. doi: 10.1111/j.1476-5381.2011.01321.x. Br J Pharmacol. 2011. PMID: 21410457 Free PMC article.

7

Structure-activity relationship and in vitro pharmacological evaluation of imidazo[1,2-a]pyridine-based inhibitors of 5-LO.

Buscató El, Wisniewska JM, Rödl CB, Brüggerhoff A, Kaiser A, Rörsch F, Kostewicz E, Wurglics M, Schubert-Zsilavecz M, Grösch S, Steinhilber D, Hofmann B, Proschak E. Buscató El, et al. Future Med Chem. 2013 May;5(8):865-80. doi: 10.4155/fmc.13.72. Future Med Chem. 2013. PMID: 23682565

8

Small molecules with anti-inflammatory properties in clinical development.

Hanke T, Merk D, Steinhilber D, Geisslinger G, Schubert-Zsilavecz M. Hanke T, et al. Pharmacol Ther. 2016 Jan;157:163-87. doi: 10.1016/j.pharmthera.2015.11.011. Epub 2015 Nov 26. Pharmacol Ther. 2016. PMID: 26627986 Review.

9

Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles.

Kretschmer SB, Woltersdorf S, Vogt D, Lillich FF, Rühl M, Karas M, Maucher IV, Roos J, Häfner AK, Kaiser A, Wurglics M, Schubert-Zsilavecz M, Angioni C, Geisslinger G, Stark H, Steinhilber D, Hofmann B. Kretschmer SB, et al. Biochem Pharmacol. 2017 Jan 1;123:52-62. doi: 10.1016/j.bcp.2016.09.021. Epub 2016 Sep 23. Biochem Pharmacol. 2017. PMID: 27671344

10

Truxillic acid derivatives act as peroxisome proliferator-activated receptor gamma activators.

Steri R, Rupp M, Proschak E, Schroeter T, Zettl H, Hansen K, Schwarz O, Müller-Kuhrt L, Müller KR, Schneider G, Schubert-Zsilavecz M. Steri R, et al. Bioorg Med Chem Lett. 2010 May 1;20(9):2920-3. doi: 10.1016/j.bmcl.2010.03.026. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20347594

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