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Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis.
Lievens D, Zernecke A, Seijkens T, Soehnlein O, Beckers L, Munnix IC, Wijnands E, Goossens P, van Kruchten R, Thevissen L, Boon L, Flavell RA, Noelle RJ, Gerdes N, Biessen EA, Daemen MJ, Heemskerk JW, Weber C, Lutgens E. Lievens D, et al. Among authors: flavell ra. Blood. 2010 Nov 18;116(20):4317-27. doi: 10.1182/blood-2010-01-261206. Epub 2010 Aug 12. Blood. 2010. PMID: 20705757 Free PMC article.
Sensing DNA as danger: The discovery of cGAS.
Flavell RA, Sefik E. Flavell RA, et al. Immunity. 2024 Oct 8;57(10):2251-2254. doi: 10.1016/j.immuni.2024.09.009. Epub 2024 Sep 19. Immunity. 2024. PMID: 39303723
The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity.
Marin-Lopez A, Huck JD, Esterly AT, Azcutia V, Rosen C, Garcia-Milian R, Sefik E, Vidal-Pedrola G, Raduwan H, Chen TY, Arora G, Halene S, Shaw AC, Palm NW, Flavell RA, Parkos CA, Thangamani S, Ring AM, Fikrig E. Marin-Lopez A, et al. Among authors: flavell ra. Sci Immunol. 2024 Aug 9;9(98):eadk9872. doi: 10.1126/sciimmunol.adk9872. Epub 2024 Aug 9. Sci Immunol. 2024. PMID: 39121194
UBXN3B is crucial for B lymphopoiesis.
Geng T, Yang D, Lin T, Harrison AG, Wang B, Cao Z, Torrance B, Fan Z, Wang K, Wang Y, Yang L, Haynes L, Cheng G, Vella AT, Flavell RA, Pereira JP, Fikrig E, Wang P. Geng T, et al. Among authors: flavell ra. EBioMedicine. 2024 Aug;106:105248. doi: 10.1016/j.ebiom.2024.105248. Epub 2024 Jul 16. EBioMedicine. 2024. PMID: 39018756 Free PMC article.
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.
Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Mertens RT, et al. Among authors: flavell ra. Immunity. 2024 Sep 10;57(9):2077-2094.e12. doi: 10.1016/j.immuni.2024.06.001. Epub 2024 Jun 20. Immunity. 2024. PMID: 38906145
IL-4 Licenses B Cell Activation Through Cholesterol Synthesis.
Steach HR, York AG, Skadow MH, Chen S, Zhao J, Williams KJ, Zhou Q, Hsieh WY, Brewer JR, Qu R, Shyer JA, Harman C, Sefik E, Mowell WK, Bailis W, Cui C, Kluger Y, Bensinger SJ, Craft J, Flavell RA. Steach HR, et al. Among authors: flavell ra. bioRxiv [Preprint]. 2024 May 15:2024.05.13.593964. doi: 10.1101/2024.05.13.593964. bioRxiv. 2024. PMID: 38798553 Free PMC article. Preprint.
1,217 results