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The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism.
Zheng X, Vittar NB, Gai X, Fernandez-Barrena MG, Moser CD, Hu C, Almada LL, McCleary-Wheeler AL, Elsawa SF, Vrabel AM, Shire AM, Comba A, Thorgeirsson SS, Kim Y, Liu Q, Fernandez-Zapico ME, Roberts LR. Zheng X, et al. PLoS One. 2012;7(11):e49581. doi: 10.1371/journal.pone.0049581. Epub 2012 Nov 19. PLoS One. 2012. PMID: 23185371 Free PMC article.
Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.
Nakamura I, Fernandez-Barrena MG, Ortiz-Ruiz MC, Almada LL, Hu C, Elsawa SF, Mills LD, Romecin PA, Gulaid KH, Moser CD, Han JJ, Vrabel A, Hanse EA, Akogyeram NA, Albrecht JH, Monga SPS, Sanderson SO, Prieto J, Roberts LR, Fernandez-Zapico ME. Nakamura I, et al. J Biol Chem. 2013 Jul 19;288(29):21389-21398. doi: 10.1074/jbc.M112.443440. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23740243 Free PMC article.
The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner.
Nye MD, Almada LL, Fernandez-Barrena MG, Marks DL, Elsawa SF, Vrabel A, Tolosa EJ, Ellenrieder V, Fernandez-Zapico ME. Nye MD, et al. J Biol Chem. 2014 May 30;289(22):15495-506. doi: 10.1074/jbc.M113.545194. Epub 2014 Apr 16. J Biol Chem. 2014. PMID: 24739390 Free PMC article.
181 results