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The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation.
Lai JP, Oseini AM, Moser CD, Yu C, Elsawa SF, Hu C, Nakamura I, Han T, Aderca I, Isomoto H, Garrity-Park MM, Shire AM, Li J, Sanderson SO, Adjei AA, Fernandez-Zapico ME, Roberts LR. Lai JP, et al. Among authors: isomoto h. Hepatology. 2010 Nov;52(5):1680-9. doi: 10.1002/hep.23848. Hepatology. 2010. PMID: 20725905 Free PMC article.
Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR. Lai JP, et al. Among authors: isomoto h. Hepatology. 2008 Apr;47(4):1211-22. doi: 10.1002/hep.22202. Hepatology. 2008. PMID: 18318435 Free PMC article.
Proteasome inhibition attenuates hepatic injury in the bile duct-ligated mouse.
Anan A, Baskin-Bey ES, Isomoto H, Mott JL, Bronk SF, Albrecht JH, Gores GJ. Anan A, et al. Among authors: isomoto h. Am J Physiol Gastrointest Liver Physiol. 2006 Oct;291(4):G709-16. doi: 10.1152/ajpgi.00126.2006. Epub 2006 Jun 22. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16798723 Free article.
569 results