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Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.
Martini PG, Cook LC, Alderucci S, Norton AW, Lundberg DM, Fish SM, Langsetmo K, Jönsson G, Lood C, Gullstrand B, Zaleski KJ, Savioli N, Lottherand J, Bedard C, Gill J, Concino MF, Heartlein MW, Truedsson L, Powell JL, Tzianabos AO. Martini PG, et al. Among authors: norton aw. BMC Immunol. 2010 Aug 20;11:43. doi: 10.1186/1471-2172-11-43. BMC Immunol. 2010. PMID: 20727163 Free PMC article.
Expression, purification, and characterization of human mannose-6-phosphate receptor - Extra cellular domain from a stable cell line utilizing a small molecule biomimetic of the mannose-6-phosphate moiety.
Dwyer B, Lundberg D, Iskenderian A, Strack-Logue B, Pescatore B, Norton AW, Xu J, Meiyappan M, Concino MF, Zhang B. Dwyer B, et al. Among authors: norton aw. Protein Expr Purif. 2020 Jun;170:105589. doi: 10.1016/j.pep.2020.105589. Epub 2020 Feb 3. Protein Expr Purif. 2020. PMID: 32027983 Free article.
Protein Engineering on Human Recombinant Follistatin: Enhancing Pharmacokinetic Characteristics for Therapeutic Application.
Shen C, Iskenderian A, Lundberg D, He T, Palmieri K, Crooker R, Deng Q, Traylor M, Gu S, Rong H, Ehmann D, Pescatore B, Strack-Logue B, Romashko A, Baviello G, Gill J, Zhang B, Meiyappan M, Pan C, Norton AW. Shen C, et al. Among authors: norton aw. J Pharmacol Exp Ther. 2018 Aug;366(2):291-302. doi: 10.1124/jpet.118.248195. Epub 2018 May 11. J Pharmacol Exp Ther. 2018. PMID: 29752426
Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone.
Iskenderian A, Liu N, Deng Q, Huang Y, Shen C, Palmieri K, Crooker R, Lundberg D, Kastrapeli N, Pescatore B, Romashko A, Dumas J, Comeau R, Norton A, Pan J, Rong H, Derakhchan K, Ehmann DE. Iskenderian A, et al. Skelet Muscle. 2018 Oct 27;8(1):34. doi: 10.1186/s13395-018-0180-z. Skelet Muscle. 2018. PMID: 30368252 Free PMC article.
Vascular Endothelial Growth Factor Enhances Compensatory Lung Growth in Piglets.
Dao DT, Anez-Bustillos L, Pan A, O'Loughlin AA, Mitchell PD, Fell GL, Baker MA, Cho BS, Nandivada P, Nedder AP, Smithers CJ, Chen N, Comeau R, Holmes K, Kalled S, Norton A, Zhang B, Puder M. Dao DT, et al. Surgery. 2018 Dec;164(6):1279-1286. doi: 10.1016/j.surg.2018.07.003. Epub 2018 Sep 5. Surgery. 2018. PMID: 30193736 Free PMC article.
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