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21 results

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Page 1
Discovery of quinolines as selective glucocorticoid receptor agonists.
Jaroch S, Berger M, Huwe C, Krolikiewicz K, Rehwinkel H, Schäcke H, Schmees N, Skuballa W. Jaroch S, et al. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5835-8. doi: 10.1016/j.bmcl.2010.07.125. Epub 2010 Aug 3. Bioorg Med Chem Lett. 2010. PMID: 20727743
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects.
Schäcke H, Schottelius A, Döcke WD, Strehlke P, Jaroch S, Schmees N, Rehwinkel H, Hennekes H, Asadullah K. Schäcke H, et al. Among authors: jaroch s. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):227-32. doi: 10.1073/pnas.0300372101. Epub 2003 Dec 23. Proc Natl Acad Sci U S A. 2004. PMID: 14694204 Free PMC article.
Discovery of new selective glucocorticoid receptor agonist leads.
Berger M, Rehwinkel H, Schmees N, Schäcke H, Edman K, Wissler L, Reichel A, Jaroch S. Berger M, et al. Among authors: jaroch s. Bioorg Med Chem Lett. 2017 Feb 1;27(3):437-442. doi: 10.1016/j.bmcl.2016.12.047. Epub 2016 Dec 23. Bioorg Med Chem Lett. 2017. PMID: 28043796
SEGRAs: a novel class of anti-inflammatory compounds.
Schäcke H, Hennekes H, Schottelius A, Jaroch S, Lehmann M, Schmees N, Rehwinkel H, Asadullah K. Schäcke H, et al. Among authors: jaroch s. Ernst Schering Res Found Workshop. 2002;(40):357-71. doi: 10.1007/978-3-662-04660-9_20. Ernst Schering Res Found Workshop. 2002. PMID: 12355726 Review.
Dihydroquinolines as novel n-NOS inhibitors.
Jaroch S, Hölscher P, Rehwinkel H, Sülzle D, Burton G, Hillmann M, McDonald FM. Jaroch S, et al. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2561-4. doi: 10.1016/s0960-894x(02)00481-x. Bioorg Med Chem Lett. 2002. PMID: 12182860
Fluorinated dihydroquinolines as potent n-NOS inhibitors.
Jaroch S, Rehwinkel H, Hölscher P, Sülzle D, Burton G, Hillmann M, McDonald FM, Miklautz H. Jaroch S, et al. Bioorg Med Chem Lett. 2004 Feb 9;14(3):743-6. doi: 10.1016/j.bmcl.2003.11.022. Bioorg Med Chem Lett. 2004. PMID: 14741281
Differential inhibition of inducible T cell cytokine secretion by potent iron chelators.
Leung S, Holbrook A, King B, Lu HT, Evans V, Miyamoto N, Mallari C, Harvey S, Davey D, Ho E, Li WW, Parkinson J, Horuk R, Jaroch S, Berger M, Skuballa W, West C, Pulk R, Phillips G, Bryant J, Subramanyam B, Schaefer C, Salamon H, Lyons E, Schilling D, Seidel H, Kraetzschmar J, Snider M, Perez D. Leung S, et al. Among authors: jaroch s. J Biomol Screen. 2005 Mar;10(2):157-67. doi: 10.1177/1087057104272394. J Biomol Screen. 2005. PMID: 15799959
21 results