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Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
Dunlop DC, Bonomelli C, Mansab F, Vasiljevic S, Doores KJ, Wormald MR, Palma AS, Feizi T, Harvey DJ, Dwek RA, Crispin M, Scanlan CN. Dunlop DC, et al. Among authors: bonomelli c. Glycobiology. 2010 Jul;20(7):812-23. doi: 10.1093/glycob/cwq020. Epub 2010 Feb 24. Glycobiology. 2010. PMID: 20181792 Free PMC article.
Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: application to glycans from engineered glycoforms of intact, folded HIV gp120.
Harvey DJ, Sobott F, Crispin M, Wrobel A, Bonomelli C, Vasiljevic S, Scanlan CN, Scarff CA, Thalassinos K, Scrivens JH. Harvey DJ, et al. Among authors: bonomelli c. J Am Soc Mass Spectrom. 2011 Mar;22(3):568-81. doi: 10.1007/s13361-010-0053-0. Epub 2011 Feb 8. J Am Soc Mass Spectrom. 2011. PMID: 21472575
Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
Pritchard LK, Spencer DI, Royle L, Bonomelli C, Seabright GE, Behrens AJ, Kulp DW, Menis S, Krumm SA, Dunlop DC, Crispin DJ, Bowden TA, Scanlan CN, Ward AB, Schief WR, Doores KJ, Crispin M. Pritchard LK, et al. Among authors: bonomelli c. Nat Commun. 2015 Jun 24;6:7479. doi: 10.1038/ncomms8479. Nat Commun. 2015. PMID: 26105115 Free PMC article.
18 results