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A new NF-κB inhibitor based on the amino-epoxyquinol core of DHMEQ.
Saitoh T, Shimada C, Takeiri M, Shiino M, Ohba S, Obata R, Ishikawa Y, Umezawa K, Nishiyama S. Saitoh T, et al. Among authors: ishikawa y. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5638-42. doi: 10.1016/j.bmcl.2010.08.036. Epub 2010 Aug 11. Bioorg Med Chem Lett. 2010. PMID: 20801656
Efficient synthesis of (+/-)-parasitenone, a novel inhibitor of NF-kappaB.
Saitoh T, Suzuki E, Takasugi A, Obata R, Ishikawa Y, Umezawa K, Nishiyama S. Saitoh T, et al. Among authors: ishikawa y. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5383-6. doi: 10.1016/j.bmcl.2009.07.120. Epub 2009 Jul 30. Bioorg Med Chem Lett. 2009. PMID: 19666224
Inhibition of macrophage activation and suppression of graft rejection by DTCM-glutarimide, a novel piperidine derived from the antibiotic 9-methylstreptimidone.
Takeiri M, Tachibana M, Kaneda A, Ito A, Ishikawa Y, Nishiyama S, Goto R, Yamashita K, Shibasaki S, Hirokata G, Ozaki M, Todo S, Umezawa K. Takeiri M, et al. Among authors: ishikawa y. Inflamm Res. 2011 Sep;60(9):879-88. doi: 10.1007/s00011-011-0348-z. Epub 2011 May 28. Inflamm Res. 2011. PMID: 21625968
Total syntheses of amphidinolides B, G, and H.
Hara A, Morimoto R, Iwasaki Y, Saitoh T, Ishikawa Y, Nishiyama S. Hara A, et al. Among authors: ishikawa y. Angew Chem Int Ed Engl. 2012 Sep 24;51(39):9877-80. doi: 10.1002/anie.201204992. Epub 2012 Aug 24. Angew Chem Int Ed Engl. 2012. PMID: 22927025
3,756 results