Furet P - Search Results

1

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis.

Martiny-Baron G, Holzer P, Billy E, Schnell C, Brueggen J, Ferretti M, Schmiedeberg N, Wood JM, Furet P, Imbach P. Martiny-Baron G, et al. Among authors: furet p. Angiogenesis. 2010 Sep;13(3):259-67. doi: 10.1007/s10456-010-9183-z. Epub 2010 Aug 29. Angiogenesis. 2010. PMID: 20803239 Free PMC article.

2

2,6,9-trisubstituted purines: optimization towards highly potent and selective CDK1 inhibitors.

Imbach P, Capraro HG, Furet P, Mett H, Meyer T, Zimmermann J. Imbach P, et al. Among authors: furet p. Bioorg Med Chem Lett. 1999 Jan 4;9(1):91-6. doi: 10.1016/s0960-894x(98)00691-x. Bioorg Med Chem Lett. 1999. PMID: 9990463

3

New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.

Bold G, Altmann KH, Frei J, Lang M, Manley PW, Traxler P, Wietfeld B, Brüggen J, Buchdunger E, Cozens R, Ferrari S, Furet P, Hofmann F, Martiny-Baron G, Mestan J, Rösel J, Sills M, Stover D, Acemoglu F, Boss E, Emmenegger R, Lässer L, Masso E, Roth R, Schlachter C, Vetterli W. Bold G, et al. Among authors: furet p. J Med Chem. 2000 Jun 15;43(12):2310-23. doi: 10.1021/jm9909443. J Med Chem. 2000. PMID: 10882357

4

Structure-based design of potent CDK1 inhibitors derived from olomoucine.

Furet P, Zimmermann J, Capraro HG, Meyer T, Imbach P. Furet P, et al. J Comput Aided Mol Des. 2000 Jul;14(5):403-9. doi: 10.1023/a:1008115004986. J Comput Aided Mol Des. 2000. PMID: 10896313

5

Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.

Soni R, O'Reilly T, Furet P, Muller L, Stephan C, Zumstein-Mecker S, Fretz H, Fabbro D, Chaudhuri B. Soni R, et al. Among authors: furet p. J Natl Cancer Inst. 2001 Mar 21;93(6):436-46. doi: 10.1093/jnci/93.6.436. J Natl Cancer Inst. 2001. PMID: 11259469

6

A new structural class of selective and non-covalent inhibitors of the chymotrypsin-like activity of the 20S proteasome.

García-Echeverría C, Imbach P, France D, Fürst P, Lang M, Noorani AM, Scholz D, Zimmermann J, Furet P. García-Echeverría C, et al. Among authors: furet p. Bioorg Med Chem Lett. 2001 May 21;11(10):1317-9. doi: 10.1016/s0960-894x(01)00205-0. Bioorg Med Chem Lett. 2001. PMID: 11392545

7

Modeling of the binding mode of a non-covalent inhibitor of the 20S proteasome. Application to structure-based analogue design.

Furet P, Imbach P, Fürst P, Lang M, Noorani M, Zimmermann J, García-Echeverria C. Furet P, et al. Bioorg Med Chem Lett. 2001 May 21;11(10):1321-4. doi: 10.1016/s0960-894x(01)00206-2. Bioorg Med Chem Lett. 2001. PMID: 11392546

8

Tyrosine kinase inhibitors: from rational design to clinical trials.

Traxler P, Bold G, Buchdunger E, Caravatti G, Furet P, Manley P, O'Reilly T, Wood J, Zimmermann J. Traxler P, et al. Among authors: furet p. Med Res Rev. 2001 Nov;21(6):499-512. doi: 10.1002/med.1022. Med Res Rev. 2001. PMID: 11607931 Review.

9

Structure-based optimisation of 2-aminobenzylstatine derivatives: potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome.

Furet P, Imbach P, Fuerst P, Lang M, Noorani M, Zimmermann J, García-Echeverría C. Furet P, et al. Bioorg Med Chem Lett. 2002 May 20;12(10):1331-4. doi: 10.1016/s0960-894x(02)00178-6. Bioorg Med Chem Lett. 2002. PMID: 11992770

10

Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors.

Manley PW, Furet P, Bold G, Brüggen J, Mestan J, Meyer T, Schnell CR, Wood J, Haberey M, Huth A, Krüger M, Menrad A, Ottow E, Seidelmann D, Siemeister G, Thierauch KH. Manley PW, et al. Among authors: furet p. J Med Chem. 2002 Dec 19;45(26):5687-93. doi: 10.1021/jm020899q. J Med Chem. 2002. PMID: 12477352

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