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A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jørgensen T, Lauritzen T, Sandbæk A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T. Yamauchi T, et al. Among authors: watada h. Nat Genet. 2010 Oct;42(10):864-8. doi: 10.1038/ng.660. Epub 2010 Sep 5. Nat Genet. 2010. PMID: 20818381
Responsiveness of insulin-induced cardiac sympathetic nerve activation associates with blood pressure regulation in diabetics.
Takagi M, Tanaka Y, Yamasaki Y, Yamamoto M, Hori M, Nakaniwa T, Niwa M, Uchino H, Tamura Y, Nomiyama T, Watada H, Kawamori R. Takagi M, et al. Among authors: watada h. Am J Physiol Endocrinol Metab. 2003 May;284(5):E1022-6. doi: 10.1152/ajpendo.00169.2002. Epub 2003 Feb 4. Am J Physiol Endocrinol Metab. 2003. PMID: 12569084 Free article.
Pdx1 expression in Irs2-deficient mouse beta-cells is regulated in a strain-dependent manner.
Suzuki R, Tobe K, Terauchi Y, Komeda K, Kubota N, Eto K, Yamauchi T, Azuma K, Kaneto H, Taguchi T, Koga T, German MS, Watada H, Kawamori R, Wright CV, Kajimoto Y, Kimura S, Nagai R, Kadowaki T. Suzuki R, et al. Among authors: watada h. J Biol Chem. 2003 Oct 31;278(44):43691-8. doi: 10.1074/jbc.M307004200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12869553 Free article.
A new En face method is useful to quantitate endothelial damage in vivo.
Azuma K, Watada H, Niihashi M, Otsuka A, Sato F, Kawasumi M, Shimada S, Tanaka Y, Kawamori R, Mitsumata M. Azuma K, et al. Among authors: watada h. Biochem Biophys Res Commun. 2003 Sep 19;309(2):384-90. doi: 10.1016/j.bbrc.2003.08.013. Biochem Biophys Res Commun. 2003. PMID: 12951061
Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1.
Nomiyama T, Igarashi Y, Taka H, Mineki R, Uchida T, Ogihara T, Choi JB, Uchino H, Tanaka Y, Maegawa H, Kashiwagi A, Murayama K, Kawamori R, Watada H. Nomiyama T, et al. Among authors: watada h. Biochem Biophys Res Commun. 2004 Jul 30;320(3):639-47. doi: 10.1016/j.bbrc.2004.06.019. Biochem Biophys Res Commun. 2004. PMID: 15240096
548 results