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The sympathetic nervous system induces a metastatic switch in primary breast cancer.
Sloan EK, Priceman SJ, Cox BF, Yu S, Pimentel MA, Tangkanangnukul V, Arevalo JM, Morizono K, Karanikolas BD, Wu L, Sood AK, Cole SW. Sloan EK, et al. Among authors: cox bf. Cancer Res. 2010 Sep 15;70(18):7042-52. doi: 10.1158/0008-5472.CAN-10-0522. Epub 2010 Sep 7. Cancer Res. 2010. PMID: 20823155 Free PMC article.
Subcutaneous checkpoint inhibition is equivalent to systemic delivery when combined with nelitolimod delivered via pressure-enabled drug delivery for depletion of intrahepatic myeloid-derived suppressor cells and control of liver metastases.
Ghosh CC, Cournoyer L, Liu Y, Ballarin A, Layman IB, LaPorte J, Morrissey M, Fraser K, Perati S, Cox BF, Yakirevich E, Treaba DO, Murtha TD, Guha P, Katz SC, Davar D. Ghosh CC, et al. Among authors: cox bf. J Immunother Cancer. 2024 Jul 22;12(7):e008837. doi: 10.1136/jitc-2024-008837. J Immunother Cancer. 2024. PMID: 39038918 Free PMC article.
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition.
Ghosh CC, Heatherton KR, Connell KPO, Alexander IS, Greer DA, LaPorte J, Guha P, Cox BF, Katz SC. Ghosh CC, et al. Among authors: cox bf. Cancer Gene Ther. 2022 Dec;29(12):1854-1865. doi: 10.1038/s41417-022-00484-z. Epub 2022 Jun 14. Cancer Gene Ther. 2022. PMID: 35697801 Free PMC article.
133 results