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Protective Non-neutralizing anti-N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated Virulence.
Izadi A, Godzwon M, Söderlund Strand A, Schmidt T, Kumlien Georén S, Drosten C, Ohlin M, Nordenfelt P. Izadi A, et al. Among authors: nordenfelt p. J Immunol. 2024 Sep 1;213(5):678-689. doi: 10.4049/jimmunol.2300675. J Immunol. 2024. PMID: 39018495 Free PMC article.
Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization.
Izadi A, Hailu A, Godzwon M, Wrighton S, Olofsson B, Schmidt T, Söderlund-Strand A, Elder E, Appelberg S, Valsjö M, Larsson O, Wendel-Hansen V, Ohlin M, Bahnan W, Nordenfelt P. Izadi A, et al. Among authors: nordenfelt p. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2217590120. doi: 10.1073/pnas.2217590120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011197 Free PMC article.
Invasive Streptococcal Infection Can Lead to the Generation of Cross-Strain Opsonic Antibodies.
de Neergaard T, Bläckberg A, Ivarsson H, Thomasson S, Kumra Ahnlide V, Chowdhury S, Khakzad H, Bahnan W, Malmström J, Rasmussen M, Nordenfelt P. de Neergaard T, et al. Among authors: nordenfelt p. Microbiol Spectr. 2022 Dec 21;10(6):e0248622. doi: 10.1128/spectrum.02486-22. Epub 2022 Oct 31. Microbiol Spectr. 2022. PMID: 36314947 Free PMC article.
A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function.
Bahnan W, Happonen L, Khakzad H, Kumra Ahnlide V, de Neergaard T, Wrighton S, André O, Bratanis E, Tang D, Hellmark T, Björck L, Shannon O, Malmström L, Malmström J, Nordenfelt P. Bahnan W, et al. Among authors: nordenfelt p. EMBO Mol Med. 2023 Feb 8;15(2):e16208. doi: 10.15252/emmm.202216208. Epub 2022 Dec 12. EMBO Mol Med. 2023. PMID: 36507602 Free PMC article.
69 results