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Page 1
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Espinosa L, Cathelin S, D'Altri T, Trimarchi T, Statnikov A, Guiu J, Rodilla V, Inglés-Esteve J, Nomdedeu J, Bellosillo B, Besses C, Abdel-Wahab O, Kucine N, Sun SC, Song G, Mullighan CC, Levine RL, Rajewsky K, Aifantis I, Bigas A. Espinosa L, et al. Among authors: kucine n. Cancer Cell. 2010 Sep 14;18(3):268-81. doi: 10.1016/j.ccr.2010.08.006. Cancer Cell. 2010. PMID: 20832754 Free PMC article.
Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis.
Koppikar P, Abdel-Wahab O, Hedvat C, Marubayashi S, Patel J, Goel A, Kucine N, Gardner JR, Combs AP, Vaddi K, Haley PJ, Burn TC, Rupar M, Bromberg JF, Heaney ML, de Stanchina E, Fridman JS, Levine RL. Koppikar P, et al. Among authors: kucine n. Blood. 2010 Apr 8;115(14):2919-27. doi: 10.1182/blood-2009-04-218842. Epub 2010 Feb 12. Blood. 2010. PMID: 20154217 Free PMC article.
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.
Kucine N, Marubayashi S, Bhagwat N, Papalexi E, Koppikar P, Sanchez Martin M, Dong L, Tallman MS, Paietta E, Wang K, He J, Lipson D, Stephens P, Miller V, Rowe JM, Teruya-Feldstein J, Mullighan CG, Ferrando AA, Krivtsov A, Armstrong S, Leung L, Ochiana SO, Chiosis G, Levine RL, Kleppe M. Kucine N, et al. Blood. 2015 Nov 26;126(22):2479-83. doi: 10.1182/blood-2015-03-635821. Epub 2015 Oct 6. Blood. 2015. PMID: 26443624 Free PMC article. Clinical Trial.
Primary thrombocytosis in children.
Kucine N, Chastain KM, Mahler MB, Bussel JB. Kucine N, et al. Haematologica. 2014 Apr;99(4):620-8. doi: 10.3324/haematol.2013.092684. Haematologica. 2014. PMID: 24688110 Free PMC article. Review.
Polycythemia vera in a 2-year-old child with a JAK2 exon 12 deletion.
Dermott SM, Kucine N, Farooqi MS, Li W, Silvey M. Dermott SM, et al. Among authors: kucine n. Pediatr Blood Cancer. 2021 Jul;68(7):e28994. doi: 10.1002/pbc.28994. Epub 2021 Mar 4. Pediatr Blood Cancer. 2021. PMID: 33661568 No abstract available.
Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms.
Mughal TI, Pemmaraju N, Radich JP, Deininger MW, Kucine N, Kiladjian JJ, Bose P, Gotlib J, Valent P, Chen CC, Barbui T, Rampal R, Verstovsek S, Koschmieder S, Saglio G, Van Etten RA. Mughal TI, et al. Among authors: kucine n. Hematol Oncol. 2019 Aug;37(3):240-252. doi: 10.1002/hon.2622. Epub 2019 Jun 20. Hematol Oncol. 2019. PMID: 31013548 Review.
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