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Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter phase IIa study.
Vajkoczy P, Meyer B, Weidauer S, Raabe A, Thome C, Ringel F, Breu V, Schmiedek P. Vajkoczy P, et al. J Neurosurg. 2005 Jul;103(1):9-17. doi: 10.3171/jns.2005.103.1.0009. J Neurosurg. 2005. PMID: 16121967 Clinical Trial.
Cerebral vasospasm: looking beyond vasoconstriction.
Hansen-Schwartz J, Vajkoczy P, Macdonald RL, Pluta RM, Zhang JH. Hansen-Schwartz J, et al. Among authors: vajkoczy p. Trends Pharmacol Sci. 2007 Jun;28(6):252-6. doi: 10.1016/j.tips.2007.04.002. Epub 2007 Apr 26. Trends Pharmacol Sci. 2007. PMID: 17466386
Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2).
Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, Raabe A, Vajkoczy P, Wanke I, Bach D, Frey A, Marr A, Roux S, Kassell N. Macdonald RL, et al. Among authors: vajkoczy p. Lancet Neurol. 2011 Jul;10(7):618-25. doi: 10.1016/S1474-4422(11)70108-9. Epub 2011 Jun 2. Lancet Neurol. 2011. PMID: 21640651 Clinical Trial.
Randomised trial of clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid hemorrhage undergoing surgical clipping (CONSCIOUS-2).
Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, Raabe A, Vajkoczy P, Wanke I, Bach D, Frey A, Marr A, Roux S, Kassell N. Macdonald RL, et al. Among authors: vajkoczy p. Acta Neurochir Suppl. 2013;115:27-31. doi: 10.1007/978-3-7091-1192-5_7. Acta Neurochir Suppl. 2013. PMID: 22890639 Clinical Trial.
789 results