Rakyan VK - Search Results

1

Finer S, Holland ML, Nanty L, Rakyan VK. Finer S, et al. Among authors: rakyan vk. Environ Mol Mutagen. 2011 Jan;52(1):1-11. doi: 10.1002/em.20590. Environ Mol Mutagen. 2011. PMID: 20839222 Review.

2

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains.

Rakyan VK, Down TA, Maslau S, Andrew T, Yang TP, Beyan H, Whittaker P, McCann OT, Finer S, Valdes AM, Leslie RD, Deloukas P, Spector TD. Rakyan VK, et al. Genome Res. 2010 Apr;20(4):434-9. doi: 10.1101/gr.103101.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219945 Free PMC article.

3

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.

Bell CG, Finer S, Lindgren CM, Wilson GA, Rakyan VK, Teschendorff AE, Akan P, Stupka E, Down TA, Prokopenko I, Morison IM, Mill J, Pidsley R; International Type 2 Diabetes 1q Consortium; Deloukas P, Frayling TM, Hattersley AT, McCarthy MI, Beck S, Hitman GA. Bell CG, et al. Among authors: rakyan vk. PLoS One. 2010 Nov 18;5(11):e14040. doi: 10.1371/journal.pone.0014040. PLoS One. 2010. PMID: 21124985 Free PMC article.

4

Epigenome-wide association studies for common human diseases.

Rakyan VK, Down TA, Balding DJ, Beck S. Rakyan VK, et al. Nat Rev Genet. 2011 Jul 12;12(8):529-41. doi: 10.1038/nrg3000. Nat Rev Genet. 2011. PMID: 21747404 Free PMC article. Review.

5

Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates.

Nanty L, Carbajosa G, Heap GA, Ratnieks F, van Heel DA, Down TA, Rakyan VK. Nanty L, et al. Among authors: rakyan vk. Genome Res. 2011 Nov;21(11):1841-50. doi: 10.1101/gr.121640.111. Epub 2011 Sep 22. Genome Res. 2011. PMID: 21940836 Free PMC article.

6

Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis.

Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D, Daunay A, Busato F, Mein CA, Manfras B, Dias KR, Bell CG, Tost J, Boehm BO, Beck S, Leslie RD. Rakyan VK, et al. PLoS Genet. 2011 Sep;7(9):e1002300. doi: 10.1371/journal.pgen.1002300. Epub 2011 Sep 29. PLoS Genet. 2011. PMID: 21980303 Free PMC article.

7

Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes.

Proudhon C, Duffié R, Ajjan S, Cowley M, Iranzo J, Carbajosa G, Saadeh H, Holland ML, Oakey RJ, Rakyan VK, Schulz R, Bourc'his D. Proudhon C, et al. Among authors: rakyan vk. Mol Cell. 2012 Sep 28;47(6):909-20. doi: 10.1016/j.molcel.2012.07.010. Epub 2012 Aug 16. Mol Cell. 2012. PMID: 22902559 Free PMC article.

8

Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans.

Beyan H, Down TA, Ramagopalan SV, Uvebrant K, Nilsson A, Holland ML, Gemma C, Giovannoni G, Boehm BO, Ebers GC, Lernmark Å, Cilio CM, Leslie RD, Rakyan VK. Beyan H, et al. Among authors: rakyan vk. Genome Res. 2012 Nov;22(11):2138-45. doi: 10.1101/gr.134304.111. Epub 2012 Aug 23. Genome Res. 2012. PMID: 22919074 Free PMC article.

9

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies.

Lowe R, Gemma C, Beyan H, Hawa MI, Bazeos A, Leslie RD, Montpetit A, Rakyan VK, Ramagopalan SV. Lowe R, et al. Among authors: rakyan vk. Epigenetics. 2013 Apr;8(4):445-54. doi: 10.4161/epi.24362. Epub 2013 Mar 28. Epigenetics. 2013. PMID: 23538714 Free PMC article.

10

Transgenerational inheritance of non-genetically determined phenotypes.

Holland ML, Rakyan VK. Holland ML, et al. Among authors: rakyan vk. Biochem Soc Trans. 2013 Jun;41(3):769-76. doi: 10.1042/BST20130043. Biochem Soc Trans. 2013. PMID: 23697936 Review.

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