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Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury.
Herzog C, Schmitz M, Levkau B, Herrgott I, Mersmann J, Larmann J, Johanning K, Winterhalter M, Chun J, Müller FU, Echtermeyer F, Hildebrand R, Theilmeier G. Herzog C, et al. Among authors: mersmann j. Mediators Inflamm. 2010;2010:425191. doi: 10.1155/2010/425191. Epub 2011 Jan 3. Mediators Inflamm. 2010. PMID: 21274265 Free PMC article.
High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor.
Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau B. Theilmeier G, et al. Among authors: mersmann j. Circulation. 2006 Sep 26;114(13):1403-9. doi: 10.1161/CIRCULATIONAHA.105.607135. Epub 2006 Sep 18. Circulation. 2006. PMID: 16982942
43 results