Geisslinger G - Search Results

1

5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity.

Fischer AS, Metzner J, Steinbrink SD, Ulrich S, Angioni C, Geisslinger G, Steinhilber D, Maier TJ. Fischer AS, et al. Among authors: geisslinger g. Br J Pharmacol. 2010 Oct;161(4):936-49. doi: 10.1111/j.1476-5381.2010.00915.x. Br J Pharmacol. 2010. PMID: 20860670 Free PMC article.

2

Activation of c-Jun-N-terminal-kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers.

Grösch S, Tegeder I, Schilling K, Maier TJ, Niederberger E, Geisslinger G. Grösch S, et al. Among authors: geisslinger g. FASEB J. 2003 Jul;17(10):1316-8. doi: 10.1096/fj.02-0919fje. Epub 2003 May 20. FASEB J. 2003. PMID: 12759338

3

Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.

Maier TJ, Schilling K, Schmidt R, Geisslinger G, Grösch S. Maier TJ, et al. Among authors: geisslinger g. Biochem Pharmacol. 2004 Apr 15;67(8):1469-78. doi: 10.1016/j.bcp.2003.12.014. Biochem Pharmacol. 2004. PMID: 15041464

4

Effects of the selective COX-2 inhibitors celecoxib and rofecoxib on human vascular cells.

Niederberger E, Manderscheid C, Grösch S, Schmidt H, Ehnert C, Geisslinger G. Niederberger E, et al. Among authors: geisslinger g. Biochem Pharmacol. 2004 Jul 15;68(2):341-50. doi: 10.1016/j.bcp.2004.03.029. Biochem Pharmacol. 2004. PMID: 15194006

5

Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53.

Grösch S, Schilling K, Janssen A, Maier TJ, Niederberger E, Geisslinger G. Grösch S, et al. Among authors: geisslinger g. Biochem Pharmacol. 2005 Mar 1;69(5):831-9. doi: 10.1016/j.bcp.2004.11.026. Epub 2005 Jan 13. Biochem Pharmacol. 2005. PMID: 15710360

6

Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.

Maier TJ, Janssen A, Schmidt R, Geisslinger G, Grösch S. Maier TJ, et al. Among authors: geisslinger g. FASEB J. 2005 Aug;19(10):1353-5. doi: 10.1096/fj.04-3274fje. Epub 2005 Jun 9. FASEB J. 2005. PMID: 15946992

7

Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment.

Janssen A, Maier TJ, Schiffmann S, Coste O, Seegel M, Geisslinger G, Grösch S. Janssen A, et al. Among authors: geisslinger g. Eur J Pharmacol. 2006 Jul 1;540(1-3):24-33. doi: 10.1016/j.ejphar.2006.04.030. Epub 2006 May 3. Eur J Pharmacol. 2006. PMID: 16730702

8

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors.

Grösch S, Maier TJ, Schiffmann S, Geisslinger G. Grösch S, et al. Among authors: geisslinger g. J Natl Cancer Inst. 2006 Jun 7;98(11):736-47. doi: 10.1093/jnci/djj206. J Natl Cancer Inst. 2006. PMID: 16757698 Review.

9

Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition.

Brenneis C, Maier TJ, Schmidt R, Hofacker A, Zulauf L, Jakobsson PJ, Scholich K, Geisslinger G. Brenneis C, et al. Among authors: geisslinger g. FASEB J. 2006 Jul;20(9):1352-60. doi: 10.1096/fj.05-5346com. FASEB J. 2006. PMID: 16816110

10

Pharmacological and histopathological characterization of a hyperalgesia model induced by freeze lesion.

Schmidtko A, Burian M, Altis K, Hardt K, Angioni C, Schmidt R, Podda M, Geisslinger G. Schmidtko A, et al. Among authors: geisslinger g. Pain. 2007 Feb;127(3):287-295. doi: 10.1016/j.pain.2006.11.002. Epub 2006 Dec 26. Pain. 2007. PMID: 17189672 Clinical Trial.

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