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Page 1
In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target.
Vujovic A, de Rooij L, Chahi AK, Chen HT, Yee BA, Loganathan SK, Liu L, Chan DCH, Tajik A, Tsao E, Moreira S, Joshi P, Xu J, Wong N, Balde Z, Jahangiri S, Zandi S, Aigner S, Dick JE, Minden MD, Schramek D, Yeo GW, Hope KJ. Vujovic A, et al. Among authors: schramek d. Blood Cancer Discov. 2023 May 1;4(3):180-207. doi: 10.1158/2643-3230.BCD-22-0086. Blood Cancer Discov. 2023. PMID: 36763002 Free PMC article.
Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
MacLeod G, Molaei F, Haider S, Almeida MP, Lin S, Kushida M, Sureshkumar H, Bhatti JK, Lu JQ, Schramek D, Dirks PB, Angers S. MacLeod G, et al. Among authors: schramek d. Cancer Res. 2024 Dec 2;84(23):3967-3983. doi: 10.1158/0008-5472.CAN-23-4024. Cancer Res. 2024. PMID: 39186687
Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection.
Cronin SJ, Nehme NT, Limmer S, Liegeois S, Pospisilik JA, Schramek D, Leibbrandt A, Simoes Rde M, Gruber S, Puc U, Ebersberger I, Zoranovic T, Neely GG, von Haeseler A, Ferrandon D, Penninger JM. Cronin SJ, et al. Among authors: schramek d. Science. 2009 Jul 17;325(5938):340-3. doi: 10.1126/science.1173164. Epub 2009 Jun 11. Science. 2009. PMID: 19520911 Free PMC article.
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate.
Pospisilik JA, Schramek D, Schnidar H, Cronin SJ, Nehme NT, Zhang X, Knauf C, Cani PD, Aumayr K, Todoric J, Bayer M, Haschemi A, Puviindran V, Tar K, Orthofer M, Neely GG, Dietzl G, Manoukian A, Funovics M, Prager G, Wagner O, Ferrandon D, Aberger F, Hui CC, Esterbauer H, Penninger JM. Pospisilik JA, et al. Among authors: schramek d. Cell. 2010 Jan 8;140(1):148-60. doi: 10.1016/j.cell.2009.12.027. Cell. 2010. PMID: 20074523 Free article.
Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Blaas L, Kornfeld JW, Schramek D, Musteanu M, Zollner G, Gumhold J, van Zijl F, Schneller D, Esterbauer H, Egger G, Mair M, Kenner L, Mikulits W, Eferl R, Moriggl R, Penninger J, Trauner M, Casanova E. Blaas L, et al. Among authors: schramek d. Hepatology. 2010 Apr;51(4):1319-26. doi: 10.1002/hep.23469. Hepatology. 2010. PMID: 20162728 Free PMC article.
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
Neely GG, Hess A, Costigan M, Keene AC, Goulas S, Langeslag M, Griffin RS, Belfer I, Dai F, Smith SB, Diatchenko L, Gupta V, Xia CP, Amann S, Kreitz S, Heindl-Erdmann C, Wolz S, Ly CV, Arora S, Sarangi R, Dan D, Novatchkova M, Rosenzweig M, Gibson DG, Truong D, Schramek D, Zoranovic T, Cronin SJ, Angjeli B, Brune K, Dietzl G, Maixner W, Meixner A, Thomas W, Pospisilik JA, Alenius M, Kress M, Subramaniam S, Garrity PA, Bellen HJ, Woolf CJ, Penninger JM. Neely GG, et al. Among authors: schramek d. Cell. 2010 Nov 12;143(4):628-38. doi: 10.1016/j.cell.2010.09.047. Cell. 2010. PMID: 21074052 Free PMC article.
RANKL/RANK-beyond bones.
Hanada R, Hanada T, Sigl V, Schramek D, Penninger JM. Hanada R, et al. Among authors: schramek d. J Mol Med (Berl). 2011 Jul;89(7):647-56. doi: 10.1007/s00109-011-0749-z. Epub 2011 Mar 29. J Mol Med (Berl). 2011. PMID: 21445556 Review.
73 results