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Evaluation of the validity of a perfluorooctane sulfonic acid exposure reconstruction using a measured serum concentration among workers with a wide range of exposure.
Campbell JL Jr, Linakis MW, Porter AK, Rosen EM, Logan PW, Kleinschmidt SE, Andres KL, Chang S, Taiwo OA, Olsen GW, Clewell HJ 3rd, Longnecker MP. Campbell JL Jr, et al. Among authors: clewell hj 3rd. Ann Work Expo Health. 2024 Dec 19:wxae099. doi: 10.1093/annweh/wxae099. Online ahead of print. Ann Work Expo Health. 2024. PMID: 39699232
Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.
Campbell JL Jr, Clewell HJ 3rd, Van Landingham C, Gentry PR, Andersen ME. Campbell JL Jr, et al. Among authors: clewell hj 3rd. Front Pharmacol. 2023 Aug 17;14:1223808. doi: 10.3389/fphar.2023.1223808. eCollection 2023. Front Pharmacol. 2023. PMID: 37663267 Free PMC article.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Ouedraogo G, Alexander-White C, Bury D, Clewell HJ 3rd, Cronin M, Cull T, Dent M, Desprez B, Detroyer A, Ellison C, Giammanco S, Hack E, Hewitt NJ, Kenna G, Klaric M, Kreiling R, Lester C, Mahony C, Mombelli E, Naciff J, O'Brien J, Schepky A, Tozer S, van der Burg B, van Vugt-Lussenburg B, Stuard S, Cosmetics Europe. Ouedraogo G, et al. Among authors: clewell hj 3rd. Regul Toxicol Pharmacol. 2022 Jul;132:105161. doi: 10.1016/j.yrtph.2022.105161. Epub 2022 May 1. Regul Toxicol Pharmacol. 2022. PMID: 35508214 Free article.
Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms.
Andersen ME, Hagenbuch B, Apte U, Corton JC, Fletcher T, Lau C, Roth WL, Staels B, Vega GL, Clewell HJ 3rd, Longnecker MP. Andersen ME, et al. Among authors: clewell hj 3rd. Toxicology. 2021 Jul;459:152845. doi: 10.1016/j.tox.2021.152845. Epub 2021 Jul 8. Toxicology. 2021. PMID: 34246716 Free PMC article. Review.
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Bury D, Alexander-White C, Clewell HJ 3rd, Cronin M, Desprez B, Detroyer A, Efremenko A, Firman J, Hack E, Hewitt NJ, Kenna G, Klaric M, Lester C, Mahony C, Ouedraogo G, Paini A, Schepky A; Cosmetics Europe. Bury D, et al. Among authors: clewell hj 3rd. Regul Toxicol Pharmacol. 2021 Jul;123:104931. doi: 10.1016/j.yrtph.2021.104931. Epub 2021 Apr 24. Regul Toxicol Pharmacol. 2021. PMID: 33905778 Free article.
Integration of paraquat pharmacokinetic data across species using PBPK modelling.
Campbell JL Jr, Travis KZ, Clewell HJ 3rd, Stevens AJ, Hinderliter PM, Andersen ME, Botham PA, Cook AR, Minnema DJ, Wolf DC. Campbell JL Jr, et al. Among authors: clewell hj 3rd. Toxicol Appl Pharmacol. 2021 Apr 15;417:115462. doi: 10.1016/j.taap.2021.115462. Epub 2021 Feb 22. Toxicol Appl Pharmacol. 2021. PMID: 33631233 Free article.
Paraquat pharmacokinetics in primates and extrapolation to humans.
Stevens AJ, Campbell JL Jr, Travis KZ, Clewell HJ 3rd, Hinderliter PM, Botham PA, Cook AR, Minnema DJ, Wolf DC. Stevens AJ, et al. Among authors: clewell hj 3rd. Toxicol Appl Pharmacol. 2021 Apr 15;417:115463. doi: 10.1016/j.taap.2021.115463. Epub 2021 Feb 22. Toxicol Appl Pharmacol. 2021. PMID: 33631232 Free article.
156 results