Williams CM - Search Results

1

Opposing structural changes in two symmetrical polypeptides bring about opposing changes to the thermal stability of a complex integral membrane protein.

Holden-Dye K, Crouch LI, Williams CM, Bone RA, Cheng J, Böhles F, Heathcote P, Jones MR. Holden-Dye K, et al. Among authors: williams cm. Arch Biochem Biophys. 2011 Jan 15;505(2):160-70. doi: 10.1016/j.abb.2010.09.029. Epub 2010 Oct 8. Arch Biochem Biophys. 2011. PMID: 20933495

2

Structural responses to cavity-creating mutations in an integral membrane protein.

Fyfe PK, Potter JA, Cheng J, Williams CM, Watson AJ, Jones MR. Fyfe PK, et al. Among authors: williams cm. Biochemistry. 2007 Sep 18;46(37):10461-72. doi: 10.1021/bi701085w. Epub 2007 Aug 21. Biochemistry. 2007. PMID: 17711306

3

Engineering protein stability with atomic precision in a monomeric miniprotein.

Baker EG, Williams C, Hudson KL, Bartlett GJ, Heal JW, Porter Goff KL, Sessions RB, Crump MP, Woolfson DN. Baker EG, et al. Nat Chem Biol. 2017 Jul;13(7):764-770. doi: 10.1038/nchembio.2380. Epub 2017 May 22. Nat Chem Biol. 2017. PMID: 28530710 Free PMC article.

4

Small-residue packing motifs modulate the structure and function of a minimal de novo membrane protein.

Curnow P, Hardy BJ, Dufour V, Arthur CJ, Stenner R, Hodgson LR, Verkade P, Williams C, Shoemark DK, Sessions RB, Crump MP, Jones MR, Anderson JLR. Curnow P, et al. Sci Rep. 2020 Sep 16;10(1):15203. doi: 10.1038/s41598-020-71585-8. Sci Rep. 2020. PMID: 32938984 Free PMC article.

5

Solution structure of an acyl carrier protein domain from a fungal type I polyketide synthase.

Wattana-amorn P, Williams C, Płoskoń E, Cox RJ, Simpson TJ, Crosby J, Crump MP. Wattana-amorn P, et al. Biochemistry. 2010 Mar 16;49(10):2186-93. doi: 10.1021/bi902176v. Biochemistry. 2010. PMID: 20136099

6

Analysis of Streptomyces coelicolor phosphopantetheinyl transferase, AcpS, reveals the basis for relaxed substrate specificity.

Dall'aglio P, Arthur CJ, Williams C, Vasilakis K, Maple HJ, Crosby J, Crump MP, Hadfield AT. Dall'aglio P, et al. Biochemistry. 2011 Jun 28;50(25):5704-17. doi: 10.1021/bi2003668. Epub 2011 Jun 6. Biochemistry. 2011. PMID: 21595442

7

The de novo design of a biocompatible and functional integral membrane protein using minimal sequence complexity.

Lalaurie CJ, Dufour V, Meletiou A, Ratcliffe S, Harland A, Wilson O, Vamasiri C, Shoemark DK, Williams C, Arthur CJ, Sessions RB, Crump MP, Anderson JLR, Curnow P. Lalaurie CJ, et al. Sci Rep. 2018 Oct 1;8(1):14564. doi: 10.1038/s41598-018-31964-8. Sci Rep. 2018. PMID: 30275547 Free PMC article.

8

Stabilizing and Understanding a Miniprotein by Rational Redesign.

Porter Goff KL, Nicol D, Williams C, Crump MP, Zieleniewski F, Samphire JL, Baker EG, Woolfson DN. Porter Goff KL, et al. Biochemistry. 2019 Jul 16;58(28):3060-3064. doi: 10.1021/acs.biochem.9b00067. Epub 2019 Jul 8. Biochemistry. 2019. PMID: 31251570

9

Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11.

Williams C, Rezgui D, Prince SN, Zaccheo OJ, Foulstone EJ, Forbes BE, Norton RS, Crosby J, Hassan AB, Crump MP. Williams C, et al. Structure. 2007 Sep;15(9):1065-78. doi: 10.1016/j.str.2007.07.007. Structure. 2007. PMID: 17850746 Free article.

10

An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.

Evans SE, Williams C, Arthur CJ, Burston SG, Simpson TJ, Crosby J, Crump MP. Evans SE, et al. Chembiochem. 2008 Oct 13;9(15):2424-32. doi: 10.1002/cbic.200800180. Chembiochem. 2008. PMID: 18770515

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