Rosa T - Search Results

1

Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.

Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ, Rosa T, Romano LC, Zou B, O'Donnell CP, Stewart AF, Garcia-Ocaña A, Alonso LC. Levitt HE, et al. Among authors: rosa t. Diabetologia. 2011 Mar;54(3):572-82. doi: 10.1007/s00125-010-1919-1. Epub 2010 Oct 9. Diabetologia. 2011. PMID: 20936253 Free PMC article.

2

Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.

Yokoe T, Alonso LC, Romano LC, Rosa TC, O'Doherty RM, Garcia-Ocana A, Minoguchi K, O'Donnell CP. Yokoe T, et al. Among authors: rosa tc. J Physiol. 2008 Feb 1;586(3):899-911. doi: 10.1113/jphysiol.2007.143586. Epub 2007 Nov 22. J Physiol. 2008. PMID: 18033815 Free PMC article.

3

Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.

Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC, Garcia-Ocaña A. Mellado-Gil J, et al. Diabetes. 2011 Feb;60(2):525-36. doi: 10.2337/db09-1305. Epub 2010 Oct 27. Diabetes. 2011. PMID: 20980460 Free PMC article.

4

Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.

Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A. Velazquez-Garcia S, et al. Diabetes. 2011 Oct;60(10):2546-59. doi: 10.2337/db10-1783. Epub 2011 Sep 12. Diabetes. 2011. PMID: 21911744 Free PMC article.

5

Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis.

González-Pertusa JA, Dubé J, Valle SR, Rosa TC, Takane KK, Mellado-Gil JM, Perdomo G, Vasavada RC, García-Ocaña A. González-Pertusa JA, et al. Endocrinology. 2010 Apr;151(4):1487-98. doi: 10.1210/en.2009-0975. Epub 2010 Feb 22. Endocrinology. 2010. PMID: 20176723 Free PMC article.

6

Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.

Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, García-Ocana A. Demirci C, et al. Among authors: rosa t. Diabetes. 2012 May;61(5):1143-52. doi: 10.2337/db11-1154. Epub 2012 Mar 16. Diabetes. 2012. PMID: 22427375 Free PMC article.

7

Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis.

Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A. Vasavada RC, et al. Diabetes. 2007 Nov;56(11):2732-43. doi: 10.2337/db07-0461. Epub 2007 Aug 8. Diabetes. 2007. PMID: 17686945

8

Hyperinsulinemia predicts survival in a hyperglycemic mouse model of critical illness.

Woodske ME, Yokoe T, Zou B, Romano LC, Rosa TC, Garcia-Ocana A, Alonso LC, O'Donnell CP, McVerry BJ. Woodske ME, et al. Among authors: rosa tc. Crit Care Med. 2009 Sep;37(9):2596-603. doi: 10.1097/CCM.0b013e3181a9338a. Crit Care Med. 2009. PMID: 19623043 Free PMC article.

9

Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.

Alvarez-Perez JC, Rosa TC, Casinelli GP, Valle SR, Lakshmipathi J, Rosselot C, Rausell-Palamos F, Vasavada RC, García-Ocaña A. Alvarez-Perez JC, et al. Mol Endocrinol. 2014 Dec;28(12):2038-48. doi: 10.1210/me.2014-1207. Mol Endocrinol. 2014. PMID: 25361392 Free PMC article.

10

Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass.

Kimple ME, Moss JB, Brar HK, Rosa TC, Truchan NA, Pasker RL, Newgard CB, Casey PJ. Kimple ME, et al. J Biol Chem. 2012 Jun 8;287(24):20344-55. doi: 10.1074/jbc.M112.359745. Epub 2012 Mar 28. J Biol Chem. 2012. PMID: 22457354 Free PMC article.

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