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199 results

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Page 1
PA-824 exhibits time-dependent activity in a murine model of tuberculosis.
Ahmad Z, Peloquin CA, Singh RP, Derendorf H, Tyagi S, Ginsberg A, Grosset JH, Nuermberger EL. Ahmad Z, et al. Among authors: ginsberg a. Antimicrob Agents Chemother. 2011 Jan;55(1):239-45. doi: 10.1128/AAC.00849-10. Epub 2010 Oct 11. Antimicrob Agents Chemother. 2011. PMID: 20937781 Free PMC article.
Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patients.
Diacon AH, Dawson R, Hanekom M, Narunsky K, Maritz SJ, Venter A, Donald PR, van Niekerk C, Whitney K, Rouse DJ, Laurenzi MW, Ginsberg AM, Spigelman MK. Diacon AH, et al. Among authors: ginsberg am. Antimicrob Agents Chemother. 2010 Aug;54(8):3402-7. doi: 10.1128/AAC.01354-09. Epub 2010 May 24. Antimicrob Agents Chemother. 2010. PMID: 20498324 Free PMC article. Clinical Trial.
Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects.
Ginsberg AM, Laurenzi MW, Rouse DJ, Whitney KD, Spigelman MK. Ginsberg AM, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3720-5. doi: 10.1128/AAC.00106-09. Epub 2009 Jun 15. Antimicrob Agents Chemother. 2009. PMID: 19528280 Free PMC article. Clinical Trial.
Phase II dose-ranging trial of the early bactericidal activity of PA-824.
Diacon AH, Dawson R, du Bois J, Narunsky K, Venter A, Donald PR, van Niekerk C, Erondu N, Ginsberg AM, Becker P, Spigelman MK. Diacon AH, et al. Among authors: ginsberg am. Antimicrob Agents Chemother. 2012 Jun;56(6):3027-31. doi: 10.1128/AAC.06125-11. Epub 2012 Mar 19. Antimicrob Agents Chemother. 2012. PMID: 22430968 Free PMC article. Clinical Trial.
Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis.
Diacon AH, Dawson R, Von Groote-Bidlingmaier F, Symons G, Venter A, Donald PR, Conradie A, Erondu N, Ginsberg AM, Egizi E, Winter H, Becker P, Mendel CM. Diacon AH, et al. Among authors: ginsberg am. Antimicrob Agents Chemother. 2013 May;57(5):2199-203. doi: 10.1128/AAC.02243-12. Epub 2013 Mar 4. Antimicrob Agents Chemother. 2013. PMID: 23459487 Free PMC article. Clinical Trial.
Tuberculosis.
Pai M, Behr MA, Dowdy D, Dheda K, Divangahi M, Boehme CC, Ginsberg A, Swaminathan S, Spigelman M, Getahun H, Menzies D, Raviglione M. Pai M, et al. Among authors: ginsberg a. Nat Rev Dis Primers. 2016 Oct 27;2:16076. doi: 10.1038/nrdp.2016.76. Nat Rev Dis Primers. 2016. PMID: 27784885 Review.
Evaluation of the pharmacokinetic interaction between repeated doses of rifapentine or rifampin and a single dose of bedaquiline in healthy adult subjects.
Winter H, Egizi E, Murray S, Erondu N, Ginsberg A, Rouse DJ, Severynse-Stevens D, Pauli E. Winter H, et al. Among authors: ginsberg a. Antimicrob Agents Chemother. 2015 Feb;59(2):1219-24. doi: 10.1128/AAC.04171-14. Epub 2014 Dec 15. Antimicrob Agents Chemother. 2015. PMID: 25512422 Free PMC article. Clinical Trial.
199 results