Andersen RJ - Search Results

1

Synthetic analogues of the microtubule-stabilizing sponge alkaloid ceratamine A are more active than the natural product.

Nodwell M, Zimmerman C, Roberge M, Andersen RJ. Nodwell M, et al. Among authors: andersen rj. J Med Chem. 2010 Nov 11;53(21):7843-51. doi: 10.1021/jm101012q. J Med Chem. 2010. PMID: 20945907

2

Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation.

Anderson HJ, Coleman JE, Andersen RJ, Roberge M. Anderson HJ, et al. Among authors: andersen rj. Cancer Chemother Pharmacol. 1997;39(3):223-6. doi: 10.1007/s002800050564. Cancer Chemother Pharmacol. 1997. PMID: 8996524

3

High-throughput assay for G2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide.

Roberge M, Berlinck RG, Xu L, Anderson HJ, Lim LY, Curman D, Stringer CM, Friend SH, Davies P, Vincent I, Haggarty SJ, Kelly MT, Britton R, Piers E, Andersen RJ. Roberge M, et al. Among authors: andersen rj. Cancer Res. 1998 Dec 15;58(24):5701-6. Cancer Res. 1998. PMID: 9865726

4

Improved synthesis of isogranulatimide, a G2 checkpoint inhibitor. Syntheses Of didemnimide C, isodidemnimide A, neodidemnimide A, 17-methylgranulatimide, and isogranulatimides A-C.

Piers E, Britton R, Andersen RJ. Piers E, et al. Among authors: andersen rj. J Org Chem. 2000 Jan 28;65(2):530-5. doi: 10.1021/jo9914723. J Org Chem. 2000. PMID: 10813968

5

Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization.

Cinel B, Roberge M, Behrisch H, van Ofwegen L, Castro CB, Andersen RJ. Cinel B, et al. Among authors: andersen rj. Org Lett. 2000 Feb 10;2(3):257-60. doi: 10.1021/ol9912027. Org Lett. 2000. PMID: 10814296

6

Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts.

Roberge M, Cinel B, Anderson HJ, Lim L, Jiang X, Xu L, Bigg CM, Kelly MT, Andersen RJ. Roberge M, et al. Among authors: andersen rj. Cancer Res. 2000 Sep 15;60(18):5052-8. Cancer Res. 2000. PMID: 11016628

7

Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine.

Curman D, Cinel B, Williams DE, Rundle N, Block WD, Goodarzi AA, Hutchins JR, Clarke PR, Zhou BB, Lees-Miller SP, Andersen RJ, Roberge M. Curman D, et al. Among authors: andersen rj. J Biol Chem. 2001 May 25;276(21):17914-9. doi: 10.1074/jbc.M100728200. Epub 2001 Mar 7. J Biol Chem. 2001. PMID: 11279124 Free article.

8

Synthetic transformations of eleutherobin reveal new features of its microtubule-stabilizing pharmacophore.

Britton R, de Silva ED, Bigg CM, McHardy LM, Roberge M, Andersen RJ. Britton R, et al. Among authors: andersen rj. J Am Chem Soc. 2001 Sep 5;123(35):8632-3. doi: 10.1021/ja016459q. J Am Chem Soc. 2001. PMID: 11525686 No abstract available.

9

Inhibition of tumor cell invasion and angiogenesis by motuporamines.

Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, Karsan A, Andersen RJ, Dedhar S, Roberge M. Roskelley CD, et al. Among authors: andersen rj. Cancer Res. 2001 Sep 15;61(18):6788-94. Cancer Res. 2001. PMID: 11559552

10

G2 DNA damage checkpoint inhibition and antimitotic activity of 13-hydroxy-15-oxozoapatlin.

Rundle NT, Xu L, Andersen RJ, Roberge M. Rundle NT, et al. Among authors: andersen rj. J Biol Chem. 2001 Dec 21;276(51):48231-6. doi: 10.1074/jbc.M103990200. Epub 2001 Sep 25. J Biol Chem. 2001. PMID: 11572854 Free article.

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