Nodwell M - Search Results

1

Synthetic analogues of the microtubule-stabilizing sponge alkaloid ceratamine A are more active than the natural product.

Nodwell M, Zimmerman C, Roberge M, Andersen RJ. Nodwell M, et al. J Med Chem. 2010 Nov 11;53(21):7843-51. doi: 10.1021/jm101012q. J Med Chem. 2010. PMID: 20945907

2

Synthesis of antimitotic analogs of the microtubule stabilizing sponge alkaloid ceratamine A.

Nodwell M, Riffell JL, Roberge M, Andersen RJ. Nodwell M, et al. Org Lett. 2008 Mar 20;10(6):1051-4. doi: 10.1021/ol7030284. Epub 2008 Feb 16. Org Lett. 2008. PMID: 18278926

3

Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues.

Nodwell M, Pereira A, Riffell JL, Zimmerman C, Patrick BO, Roberge M, Andersen RJ. Nodwell M, et al. J Org Chem. 2009 Feb 6;74(3):995-1006. doi: 10.1021/jo802322s. J Org Chem. 2009. PMID: 19128042

4

Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.

Fonseca BD, Diering GH, Bidinosti MA, Dalal K, Alain T, Balgi AD, Forestieri R, Nodwell M, Rajadurai CV, Gunaratnam C, Tee AR, Duong F, Andersen RJ, Orlowski J, Numata M, Sonenberg N, Roberge M. Fonseca BD, et al. Among authors: nodwell m. J Biol Chem. 2012 May 18;287(21):17530-17545. doi: 10.1074/jbc.M112.359638. Epub 2012 Apr 2. J Biol Chem. 2012. PMID: 22474287 Free PMC article.

5

Activation of SHIP via a small molecule agonist kills multiple myeloma cells.

Kennah M, Yau TY, Nodwell M, Krystal G, Andersen RJ, Ong CJ, Mui AL. Kennah M, et al. Among authors: nodwell m. Exp Hematol. 2009 Nov;37(11):1274-83. doi: 10.1016/j.exphem.2009.08.001. Epub 2009 Aug 22. Exp Hematol. 2009. PMID: 19703514 Free article.

6

Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.

Lam KK, Zheng X, Forestieri R, Balgi AD, Nodwell M, Vollett S, Anderson HJ, Andersen RJ, Av-Gay Y, Roberge M. Lam KK, et al. Among authors: nodwell m. PLoS Pathog. 2012;8(5):e1002691. doi: 10.1371/journal.ppat.1002691. Epub 2012 May 10. PLoS Pathog. 2012. PMID: 22589723 Free PMC article.

7

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells.

Ong CJ, Ming-Lum A, Nodwell M, Ghanipour A, Yang L, Williams DE, Kim J, Demirjian L, Qasimi P, Ruschmann J, Cao LP, Ma K, Chung SW, Duronio V, Andersen RJ, Krystal G, Mui AL. Ong CJ, et al. Among authors: nodwell m. Blood. 2007 Sep 15;110(6):1942-9. doi: 10.1182/blood-2007-03-079699. Epub 2007 May 14. Blood. 2007. PMID: 17502453 Free article.

8

¹⁸F-Branched-Chain Amino Acids: Structure-Activity Relationships and PET Imaging Potential.

Nodwell MB, Yang H, Merkens H, Malik N, Čolović M, Björn Wagner, Martin RE, Bénard F, Schaffer P, Britton R. Nodwell MB, et al. J Nucl Med. 2019 Jul;60(7):1003-1009. doi: 10.2967/jnumed.118.220483. Epub 2019 Jan 25. J Nucl Med. 2019. PMID: 30683769 Free PMC article.

9

Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD.

McKinnell RM, Klein U, Linsell MS, Moran EJ, Nodwell MB, Pfeiffer JW, Thomas GR, Yu C, Jacobsen JR. McKinnell RM, et al. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2871-6. doi: 10.1016/j.bmcl.2014.04.095. Epub 2014 May 4. Bioorg Med Chem Lett. 2014. PMID: 24835980

10

Vancomycin disulfide derivatives as antibacterial agents.

Mu Y, Nodwell M, Pace JL, Shaw JP, Judice JK. Mu Y, et al. Among authors: nodwell m. Bioorg Med Chem Lett. 2004 Feb 9;14(3):735-8. doi: 10.1016/j.bmcl.2003.11.040. Bioorg Med Chem Lett. 2004. PMID: 14741279

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