Oxombre B - Search Results

1

Susceptibility to experimental autoimmune encephalomyelitis is associated with altered B-cell subsets distribution and decreased serum BAFF levels.

Lee-Chang C, Lefranc D, Salleron J, Faveeuw C, Allet C, Vermersch P, Oxombre B, Prin L. Lee-Chang C, et al. Among authors: oxombre b. Immunol Lett. 2011 Mar 30;135(1-2):108-17. doi: 10.1016/j.imlet.2010.10.006. Epub 2010 Oct 12. Immunol Lett. 2011. PMID: 20946917

2

High-affinity σ1 protein agonist reduces clinical and pathological signs of experimental autoimmune encephalomyelitis.

Oxombre B, Lee-Chang C, Duhamel A, Toussaint M, Giroux M, Donnier-Maréchal M, Carato P, Lefranc D, Zéphir H, Prin L, Melnyk P, Vermersch P. Oxombre B, et al. Br J Pharmacol. 2015 Apr;172(7):1769-82. doi: 10.1111/bph.13037. Epub 2015 Feb 10. Br J Pharmacol. 2015. PMID: 25521311 Free PMC article.

3

Safe and Efficient Sigma1 Ligand: A Potential Drug Candidate for Multiple Sclerosis.

Oxombre B, Madouri F, Journé AS, Ravez S, Woitrain E, Odou P, Duhal N, Ninni S, Montaigne D, Delhem N, Vermersch P, Melnyk P. Oxombre B, et al. Int J Mol Sci. 2022 Oct 6;23(19):11893. doi: 10.3390/ijms231911893. Int J Mol Sci. 2022. PMID: 36233193 Free PMC article.

4

Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands.

Donnier-Maréchal M, Carato P, Larchanché PE, Ravez S, Boulahjar R, Barczyk A, Oxombre B, Vermersch P, Melnyk P. Donnier-Maréchal M, et al. Among authors: oxombre b. Eur J Med Chem. 2017 Sep 29;138:964-978. doi: 10.1016/j.ejmech.2017.07.014. Epub 2017 Jul 12. Eur J Med Chem. 2017. PMID: 28756263

5

The G115S mutation associated with maturity-onset diabetes of the young impairs hepatocyte nuclear factor 4alpha activities and introduces a PKA phosphorylation site in its DNA-binding domain.

Oxombre B, Kouach M, Moerman E, Formstecher P, Laine B. Oxombre B, et al. Biochem J. 2004 Nov 1;383(Pt. 3):573-80. doi: 10.1042/BJ20040473. Biochem J. 2004. PMID: 15233628 Free PMC article.

6

Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells.

Oxombre B, Moerman E, Eeckhoute J, Formstecher P, Laine B. Oxombre B, et al. J Mol Med (Berl). 2002 Jul;80(7):423-30. doi: 10.1007/s00109-002-0340-8. Epub 2002 May 8. J Mol Med (Berl). 2002. PMID: 12110948

7

Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity.

Eeckhoute J, Oxombre B, Formstecher P, Lefebvre P, Laine B. Eeckhoute J, et al. Among authors: oxombre b. Nucleic Acids Res. 2003 Nov 15;31(22):6640-50. doi: 10.1093/nar/gkg850. Nucleic Acids Res. 2003. PMID: 14602925 Free PMC article.

8

A charter for biomedical research ethics in a progressive, caring society.

Vandoolaeghe S, Blaizot A, Boudiguet D, Bougault V, Dei Cas E, Foligne B, Goffard A, Lefranc H, Oxombre B, Trentesaux T, Vandenbunder B, Wolowczuk I, Delhaes L; “ethic and research” working group. Vandoolaeghe S, et al. Among authors: oxombre b. Philos Ethics Humanit Med. 2015 Nov 13;10:12. doi: 10.1186/s13010-015-0032-y. Philos Ethics Humanit Med. 2015. PMID: 26567128 Free PMC article.

9

TrkA overexpression enhances growth and metastasis of breast cancer cells.

Lagadec C, Meignan S, Adriaenssens E, Foveau B, Vanhecke E, Romon R, Toillon RA, Oxombre B, Hondermarck H, Le Bourhis X. Lagadec C, et al. Among authors: oxombre b. Oncogene. 2009 May 7;28(18):1960-70. doi: 10.1038/onc.2009.61. Epub 2009 Mar 30. Oncogene. 2009. PMID: 19330021

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