King HD - Search Results

1

Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors.

King HD, Meng Z, Deskus JA, Sloan CP, Gao Q, Beno BR, Kozlowski ES, Lapaglia MA, Mattson GK, Molski TF, Taber MT, Lodge NJ, Mattson RJ, Macor JE. King HD, et al. J Med Chem. 2010 Nov 11;53(21):7564-72. doi: 10.1021/jm100515z. J Med Chem. 2010. PMID: 20949929

2

Enantioselective synthesis of a highly potent selective serotonin reuptake inhibitor. An application of imidazolidinone catalysis to the alkylation of indoles with an alpha,beta-disubstituted alpha,beta-unsaturated aldehyde.

King HD, Meng Z, Denhart D, Mattson R, Kimura R, Wu D, Gao Q, Macor JE. King HD, et al. Org Lett. 2005 Aug 4;7(16):3437-40. doi: 10.1021/ol051000c. Org Lett. 2005. PMID: 16048311

3

Diaminopyrimidine and diaminopyridine 5-HT7 ligands.

Denhart DJ, Purandare AV, Catt JD, King HD, Gao A, Deskus JA, Poss MA, Stark AD, Torrente JR, Johnson G, Mattson RJ. Denhart DJ, et al. Among authors: king hd. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4249-52. doi: 10.1016/j.bmcl.2004.06.007. Bioorg Med Chem Lett. 2004. PMID: 15261280

4

Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.

Hill MD, Fang H, King HD, Iwuagwu CI, McDonald IM, Cook J, Zusi FC, Mate RA, Knox RJ, Post-Munson D, Easton A, Miller R, Lentz K, Clarke W, Benitex Y, Lodge N, Zaczek R, Denton R, Morgan D, Bristow L, Macor JE, Olson R. Hill MD, et al. Among authors: king hd. ACS Med Chem Lett. 2016 Dec 1;8(1):133-137. doi: 10.1021/acsmedchemlett.6b00471. eCollection 2017 Jan 12. ACS Med Chem Lett. 2016. PMID: 28105289 Free PMC article.

5

BR96 conjugates of highly potent anthracyclines.

King HD, Staab AJ, Pham-Kaplita K, Yurgaitis D, Firestone RA, Lasch SJ, Trail PA. King HD, et al. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2119-22. doi: 10.1016/s0960-894x(03)00375-5. Bioorg Med Chem Lett. 2003. PMID: 12798317

6

Monoclonal antibody conjugates of doxorubicin prepared with branched peptide linkers: inhibition of aggregation by methoxytriethyleneglycol chains.

King HD, Dubowchik GM, Mastalerz H, Willner D, Hofstead SJ, Firestone RA, Lasch SJ, Trail PA. King HD, et al. J Med Chem. 2002 Sep 12;45(19):4336-43. doi: 10.1021/jm020149g. J Med Chem. 2002. PMID: 12213074

7

Monoclonal antibody mediated intracellular targeting of tallysomycin S(10b).

Walker MA, King HD, Dalterio RA, Trail P, Firestone R, Dubowchik GM. Walker MA, et al. Among authors: king hd. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4323-7. doi: 10.1016/j.bmcl.2004.05.089. Bioorg Med Chem Lett. 2004. PMID: 15261295

8

Chemical Modification of Linkers Provides Stable Linker-Payloads for the Generation of Antibody-Drug Conjugates.

Poudel YB, Chowdari NS, Cheng H, Iwuagwu CI, King HD, Kotapati S, Passmore D, Rampulla R, Mathur A, Vite G, Gangwar S. Poudel YB, et al. Among authors: king hd. ACS Med Chem Lett. 2020 Sep 22;11(11):2190-2194. doi: 10.1021/acsmedchemlett.0c00325. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214828 Free PMC article.

9

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin.

Willner D, Trail PA, Hofstead SJ, King HD, Lasch SJ, Braslawsky GR, Greenfield RS, Kaneko T, Firestone RA. Willner D, et al. Among authors: king hd. Bioconjug Chem. 1993 Nov-Dec;4(6):521-7. doi: 10.1021/bc00024a015. Bioconjug Chem. 1993. PMID: 7508268

10

Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.

King HD, Yurgaitis D, Willner D, Firestone RA, Yang MB, Lasch SJ, Hellström KE, Trail PA. King HD, et al. Bioconjug Chem. 1999 Mar-Apr;10(2):279-88. doi: 10.1021/bc980100i. Bioconjug Chem. 1999. PMID: 10077478

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