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Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools.
Kumar D, Abdulovic AL, Viberg J, Nilsson AK, Kunkel TA, Chabes A. Kumar D, et al. Among authors: nilsson ak. Nucleic Acids Res. 2011 Mar;39(4):1360-71. doi: 10.1093/nar/gkq829. Epub 2010 Oct 20. Nucleic Acids Res. 2011. PMID: 20961955 Free PMC article.
Telomere length homeostasis responds to changes in intracellular dNTP pools.
Gupta A, Sharma S, Reichenbach P, Marjavaara L, Nilsson AK, Lingner J, Chabes A, Rothstein R, Chang M. Gupta A, et al. Among authors: nilsson ak. Genetics. 2013 Apr;193(4):1095-105. doi: 10.1534/genetics.112.149120. Epub 2013 Jan 18. Genetics. 2013. PMID: 23335335 Free PMC article.
Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance.
Rentoft M, Lindell K, Tran P, Chabes AL, Buckland RJ, Watt DL, Marjavaara L, Nilsson AK, Melin B, Trygg J, Johansson E, Chabes A. Rentoft M, et al. Among authors: nilsson ak. Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4723-8. doi: 10.1073/pnas.1519128113. Epub 2016 Apr 11. Proc Natl Acad Sci U S A. 2016. PMID: 27071091 Free PMC article.
Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired.
Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A. Wanrooij PH, et al. Among authors: nilsson ak. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12466-12471. doi: 10.1073/pnas.1713085114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109257 Free PMC article.
De novo dNTP production is essential for normal postnatal murine heart development.
Tran P, Wanrooij PH, Lorenzon P, Sharma S, Thelander L, Nilsson AK, Olofsson AK, Medini P, von Hofsten J, Stål P, Chabes A. Tran P, et al. Among authors: nilsson ak. J Biol Chem. 2019 Nov 1;294(44):15889-15897. doi: 10.1074/jbc.RA119.009492. Epub 2019 Jul 12. J Biol Chem. 2019. PMID: 31300555 Free PMC article.
Elimination of rNMPs from mitochondrial DNA has no effect on its stability.
Wanrooij PH, Tran P, Thompson LJ, Carvalho G, Sharma S, Kreisel K, Navarrete C, Feldberg AL, Watt DL, Nilsson AK, Engqvist MKM, Clausen AR, Chabes A. Wanrooij PH, et al. Among authors: nilsson ak. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14306-14313. doi: 10.1073/pnas.1916851117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513727 Free PMC article.
85 results