Griesinger C - Search Results

1

Bioinorganic chemistry of Parkinson's disease: structural determinants for the copper-mediated amyloid formation of alpha-synuclein.

Binolfi A, Rodriguez EE, Valensin D, D'Amelio N, Ippoliti E, Obal G, Duran R, Magistrato A, Pritsch O, Zweckstetter M, Valensin G, Carloni P, Quintanar L, Griesinger C, Fernández CO. Binolfi A, et al. Among authors: griesinger c. Inorg Chem. 2010 Nov 15;49(22):10668-79. doi: 10.1021/ic1016752. Epub 2010 Oct 22. Inorg Chem. 2010. PMID: 20964419

2

The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli.

Pappalardo L, Janausch IG, Vijayan V, Zientz E, Junker J, Peti W, Zweckstetter M, Unden G, Griesinger C. Pappalardo L, et al. Among authors: griesinger c. J Biol Chem. 2003 Oct 3;278(40):39185-8. doi: 10.1074/jbc.C300344200. Epub 2003 Aug 7. J Biol Chem. 2003. PMID: 12907689 Free article.

3

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

Fernández CO, Hoyer W, Zweckstetter M, Jares-Erijman EA, Subramaniam V, Griesinger C, Jovin TM. Fernández CO, et al. Among authors: griesinger c. EMBO J. 2004 May 19;23(10):2039-46. doi: 10.1038/sj.emboj.7600211. Epub 2004 Apr 22. EMBO J. 2004. PMID: 15103328 Free PMC article.

4

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein.

Bertoncini CW, Jung YS, Fernandez CO, Hoyer W, Griesinger C, Jovin TM, Zweckstetter M. Bertoncini CW, et al. Among authors: griesinger c. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1430-5. doi: 10.1073/pnas.0407146102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671169 Free PMC article.

5

Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease.

Rasia RM, Bertoncini CW, Marsh D, Hoyer W, Cherny D, Zweckstetter M, Griesinger C, Jovin TM, Fernández CO. Rasia RM, et al. Among authors: griesinger c. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4294-9. doi: 10.1073/pnas.0407881102. Epub 2005 Mar 14. Proc Natl Acad Sci U S A. 2005. PMID: 15767574 Free PMC article.

6

The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli.

Kneuper H, Janausch IG, Vijayan V, Zweckstetter M, Bock V, Griesinger C, Unden G. Kneuper H, et al. Among authors: griesinger c. J Biol Chem. 2005 May 27;280(21):20596-603. doi: 10.1074/jbc.M502015200. Epub 2005 Mar 21. J Biol Chem. 2005. PMID: 15781452 Free article.

7

Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions.

Mukrasch MD, Biernat J, von Bergen M, Griesinger C, Mandelkow E, Zweckstetter M. Mukrasch MD, et al. Among authors: griesinger c. J Biol Chem. 2005 Jul 1;280(26):24978-86. doi: 10.1074/jbc.M501565200. Epub 2005 Apr 26. J Biol Chem. 2005. PMID: 15855160 Free article.

8

Familial mutants of alpha-synuclein with increased neurotoxicity have a destabilized conformation.

Bertoncini CW, Fernandez CO, Griesinger C, Jovin TM, Zweckstetter M. Bertoncini CW, et al. Among authors: griesinger c. J Biol Chem. 2005 Sep 2;280(35):30649-52. doi: 10.1074/jbc.C500288200. Epub 2005 Jul 14. J Biol Chem. 2005. PMID: 16020550 Free article.

9

Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings.

Bernadó P, Bertoncini CW, Griesinger C, Zweckstetter M, Blackledge M. Bernadó P, et al. Among authors: griesinger c. J Am Chem Soc. 2005 Dec 28;127(51):17968-9. doi: 10.1021/ja055538p. J Am Chem Soc. 2005. PMID: 16366524

10

Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement.

Binolfi A, Rasia RM, Bertoncini CW, Ceolin M, Zweckstetter M, Griesinger C, Jovin TM, Fernández CO. Binolfi A, et al. Among authors: griesinger c. J Am Chem Soc. 2006 Aug 2;128(30):9893-901. doi: 10.1021/ja0618649. J Am Chem Soc. 2006. PMID: 16866548

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