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Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins.
Kraiczy P, Hellwage J, Skerka C, Becker H, Kirschfink M, Simon MM, Brade V, Zipfel PF, Wallich R. Kraiczy P, et al. Among authors: wallich r. J Biol Chem. 2004 Jan 23;279(4):2421-9. doi: 10.1074/jbc.M308343200. Epub 2003 Nov 7. J Biol Chem. 2004. PMID: 14607842 Free article.
Human pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1.
Herzberger P, Siegel C, Skerka C, Fingerle V, Schulte-Spechtel U, van Dam A, Wilske B, Brade V, Zipfel PF, Wallich R, Kraiczy P. Herzberger P, et al. Among authors: wallich r. Infect Immun. 2007 Oct;75(10):4817-25. doi: 10.1128/IAI.00532-07. Epub 2007 Jul 16. Infect Immun. 2007. PMID: 17635869 Free PMC article.
Identification and characterization of the factor H and FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease spirochete Borrelia spielmanii sp. nov.
Herzberger P, Siegel C, Skerka C, Fingerle V, Schulte-Spechtel U, Wilske B, Brade V, Zipfel PF, Wallich R, Kraiczy P. Herzberger P, et al. Among authors: wallich r. Int J Med Microbiol. 2009 Feb;299(2):141-54. doi: 10.1016/j.ijmm.2008.06.005. Epub 2008 Aug 15. Int J Med Microbiol. 2009. PMID: 18706858
Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.
Siegel C, Schreiber J, Haupt K, Skerka C, Brade V, Simon MM, Stevenson B, Wallich R, Zipfel PF, Kraiczy P. Siegel C, et al. Among authors: wallich r. J Biol Chem. 2008 Dec 12;283(50):34855-63. doi: 10.1074/jbc.M805844200. Epub 2008 Sep 29. J Biol Chem. 2008. PMID: 18824548 Free PMC article.
Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identify residues relevant for the architecture and binding of host complement regulators FHL-1 and factor H.
Kraiczy P, Hanssen-Hübner C, Kitiratschky V, Brenner C, Besier S, Brade V, Simon MM, Skerka C, Roversi P, Lea SM, Stevenson B, Wallich R, Zipfel PF. Kraiczy P, et al. Among authors: wallich r. Int J Med Microbiol. 2009 Apr;299(4):255-68. doi: 10.1016/j.ijmm.2008.09.002. Epub 2009 Jan 9. Int J Med Microbiol. 2009. PMID: 19138559
153 results