You MJ - Search Results

1

Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity.

Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, You MJ, Hirschi KK, Lozano G. Abbas HA, et al. Among authors: you mj. Cell Stem Cell. 2010 Nov 5;7(5):606-17. doi: 10.1016/j.stem.2010.09.013. Cell Stem Cell. 2010. PMID: 21040902 Free PMC article.

2

Tissue-specific and age-dependent effects of global Mdm2 loss.

Zhang Y, Xiong S, Li Q, Hu S, Tashakori M, Van Pelt C, You MJ, Pageon L, Lozano G. Zhang Y, et al. Among authors: you mj. J Pathol. 2014 Aug;233(4):380-91. doi: 10.1002/path.4368. Epub 2014 Jun 9. J Pathol. 2014. PMID: 24789767 Free PMC article.

3

Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth.

Wang L, Xiong H, Wu F, Zhang Y, Wang J, Zhao L, Guo X, Chang LJ, Zhang Y, You MJ, Koochekpour S, Saleem M, Huang H, Lu J, Deng Y. Wang L, et al. Among authors: you mj. Cell Rep. 2014 Sep 11;8(5):1461-74. doi: 10.1016/j.celrep.2014.07.053. Epub 2014 Aug 28. Cell Rep. 2014. PMID: 25176644 Free PMC article.

4

Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma.

Riley MF, You MJ, Multani AS, Lozano G. Riley MF, et al. Among authors: you mj. Oncogene. 2016 Jan 21;35(3):358-65. doi: 10.1038/onc.2015.88. Epub 2015 Apr 27. Oncogene. 2016. PMID: 25915849 Free PMC article.

5

p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.

Tashakori M, Zhang Y, Xiong S, You MJ, Lozano G. Tashakori M, et al. Among authors: you mj. Mol Cancer Res. 2016 Jan;14(1):56-65. doi: 10.1158/1541-7786.MCR-15-0346. Epub 2015 Nov 2. Mol Cancer Res. 2016. PMID: 26527653 Free PMC article.

6

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21.

Lee H, Dai F, Zhuang L, Xiao ZD, Kim J, Zhang Y, Ma L, You MJ, Wang Z, Gan B. Lee H, et al. Among authors: you mj. Oncotarget. 2016 Apr 12;7(15):19134-46. doi: 10.18632/oncotarget.8102. Oncotarget. 2016. PMID: 26992241 Free PMC article.

7

The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.

Xiong S, Pant V, Zhang Y, Aryal NK, You MJ, Kusewitt D, Lozano G. Xiong S, et al. Among authors: you mj. J Pathol. 2017 Mar;241(4):501-510. doi: 10.1002/path.4854. Epub 2017 Jan 6. J Pathol. 2017. PMID: 27925213 Free PMC article.

8

Tumorigenesis promotes Mdm4-S overexpression.

Pant V, Larsson CA, Aryal N, Xiong S, You MJ, Quintas-Cardama A, Lozano G. Pant V, et al. Among authors: you mj. Oncotarget. 2017 Apr 18;8(16):25837-25847. doi: 10.18632/oncotarget.15552. Oncotarget. 2017. PMID: 28460439 Free PMC article.

9

Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.

Zhang Y, Xiong S, Liu B, Pant V, Celii F, Chau G, Elizondo-Fraire AC, Yang P, You MJ, El-Naggar AK, Navin NE, Lozano G. Zhang Y, et al. Among authors: you mj. Nat Commun. 2018 Sep 27;9(1):3953. doi: 10.1038/s41467-018-06146-9. Nat Commun. 2018. PMID: 30262850 Free PMC article.

10

EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.

Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. Yang W, et al. Among authors: you mj. Mol Cell. 2012 Dec 14;48(5):771-84. doi: 10.1016/j.molcel.2012.09.028. Epub 2012 Nov 1. Mol Cell. 2012. PMID: 23123196 Free PMC article.

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