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Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
Hao Y, Samuels Y, Li Q, Krokowski D, Guan BJ, Wang C, Jin Z, Dong B, Cao B, Feng X, Xiang M, Xu C, Fink S, Meropol NJ, Xu Y, Conlon RA, Markowitz S, Kinzler KW, Velculescu VE, Brunengraber H, Willis JE, LaFramboise T, Hatzoglou M, Zhang GF, Vogelstein B, Wang Z. Hao Y, et al. Among authors: xu c, xu y. Nat Commun. 2016 Jun 20;7:11971. doi: 10.1038/ncomms11971. Nat Commun. 2016. PMID: 27321283 Free PMC article.
5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers.
Zhao Y, Feng X, Chen Y, Selfridge JE, Gorityala S, Du Z, Wang JM, Hao Y, Cioffi G, Conlon RA, Barnholtz-Sloan JS, Saltzman J, Krishnamurthi SS, Vinayak S, Veigl M, Xu Y, Bajor DL, Markowitz SD, Meropol NJ, Eads JR, Wang Z. Zhao Y, et al. Among authors: xu y. Cancer Res. 2020 Nov 1;80(21):4815-4827. doi: 10.1158/0008-5472.CAN-20-0600. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907836 Free PMC article. Clinical Trial.
Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma.
Vatolin S, Phillips JG, Jha BK, Govindgari S, Hu J, Grabowski D, Parker Y, Lindner DJ, Zhong F, Distelhorst CW, Smith MR, Cotta C, Xu Y, Chilakala S, Kuang RR, Tall S, Reu FJ. Vatolin S, et al. Among authors: xu y. Cancer Res. 2016 Jun 1;76(11):3340-50. doi: 10.1158/0008-5472.CAN-15-3099. Epub 2016 Apr 6. Cancer Res. 2016. PMID: 27197150
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