Qin N - Search Results

1

An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists.

Finley MF, Lubin ML, Neeper MP, Beck E, Liu Y, Flores CM, Qin N. Finley MF, et al. Among authors: qin n. Assay Drug Dev Technol. 2010 Dec;8(6):685-94. doi: 10.1089/adt.2010.0311. Epub 2010 Nov 4. Assay Drug Dev Technol. 2010. PMID: 21050074

2

A nonadherent cell-based HTS assay for N-type calcium channel using calcium 3 dye.

Lubin ML, Reitz TL, Todd MJ, Flores CM, Qin N, Xin H. Lubin ML, et al. Among authors: qin n. Assay Drug Dev Technol. 2006 Dec;4(6):689-94. doi: 10.1089/adt.2006.4.689. Assay Drug Dev Technol. 2006. PMID: 17199507

3

TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.

Qin N, Neeper MP, Liu Y, Hutchinson TL, Lubin ML, Flores CM. Qin N, et al. J Neurosci. 2008 Jun 11;28(24):6231-8. doi: 10.1523/JNEUROSCI.0504-08.2008. J Neurosci. 2008. PMID: 18550765 Free PMC article.

4

Development and validation of a secondary screening assay for TRPM8 antagonists using QPatch HT.

Beck EJ, Hutchinson TL, Qin N, Flores CM, Liu Y. Beck EJ, et al. Among authors: qin n. Assay Drug Dev Technol. 2010 Feb;8(1):63-72. doi: 10.1089/adt.2009.0214. Assay Drug Dev Technol. 2010. PMID: 20085457

5

A novel series of pyrazolylpiperidine N-type calcium channel blockers.

Subasinghe NL, Wall MJ, Winters MP, Qin N, Lubin ML, Finley MF, Brandt MR, Neeper MP, Schneider CR, Colburn RW, Flores CM, Sui Z. Subasinghe NL, et al. Among authors: qin n. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4080-3. doi: 10.1016/j.bmcl.2012.04.075. Epub 2012 May 2. Bioorg Med Chem Lett. 2012. PMID: 22608964

6

Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel.

Winters MP, Subasinghe N, Wall M, Beck E, Brandt MR, Finley MF, Liu Y, Lubin ML, Neeper MP, Qin N, Flores CM, Sui Z. Winters MP, et al. Among authors: qin n. Bioorg Med Chem Lett. 2014 May 1;24(9):2053-6. doi: 10.1016/j.bmcl.2014.03.062. Epub 2014 Mar 27. Bioorg Med Chem Lett. 2014. PMID: 24726802

7

Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors.

Winters MP, Subasinghe N, Wall M, Beck E, Brandt MR, Finley MF, Liu Y, Lubin ML, Neeper MP, Qin N, Flores CM, Sui Z. Winters MP, et al. Among authors: qin n. Bioorg Med Chem Lett. 2014 May 1;24(9):2057-61. doi: 10.1016/j.bmcl.2014.03.063. Epub 2014 Mar 28. Bioorg Med Chem Lett. 2014. PMID: 24726803

8

Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Ca_v 2.2) blockers for the treatment of pain.

Wall MJ, Subasinghe NL, Winters MP, Lubin ML, Finley MFA, Qin N, Brandt MR, Neeper MP, Schneider CR, Colburn RW, Flores CM, Sui Z. Wall MJ, et al. Among authors: qin n. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783. doi: 10.1016/j.bmcl.2018.10.007. Epub 2018 Oct 12. Bioorg Med Chem Lett. 2018. PMID: 30337231

9

Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.

Liu Y, Lubin ML, Reitz TL, Wang Y, Colburn RW, Flores CM, Qin N. Liu Y, et al. Among authors: qin n. Eur J Pharmacol. 2006 Jan 13;530(1-2):23-32. doi: 10.1016/j.ejphar.2005.11.033. Epub 2005 Dec 28. Eur J Pharmacol. 2006. PMID: 16386244

10

Inhibition of the rat brain sodium channel Nav1.2 after prolonged exposure to gabapentin.

Liu Y, Qin N, Reitz T, Wang Y, Flores CM. Liu Y, et al. Among authors: qin n. Epilepsy Res. 2006 Aug;70(2-3):263-8. doi: 10.1016/j.eplepsyres.2006.03.007. Epub 2006 Apr 18. Epilepsy Res. 2006. PMID: 16621448

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