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DNA double-strand break signaling and human disorders.
Bohgaki T, Bohgaki M, Hakem R. Bohgaki T, et al. Among authors: hakem r. Genome Integr. 2010 Nov 5;1(1):15. doi: 10.1186/2041-9414-1-15. Genome Integr. 2010. PMID: 21054854 Free PMC article.
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
Luk CT, Chan CK, Chiu F, Shi SY, Misra PS, Li YZ, Pollock-Tahiri E, Schroer SA, Desai HR, Sivasubramaniyam T, Cai EP, Krishnamurthy M, Han DJ, Chowdhury A, Aslam R, Yuen DA, Hakem A, Hakem R, Woo M. Luk CT, et al. Among authors: hakem r. Diabetes. 2023 Dec 1;72(12):1751-1765. doi: 10.2337/db22-1033. Diabetes. 2023. PMID: 37699387
Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
El Ghamrasni S, Pamidi A, Halaby MJ, Bohgaki M, Cardoso R, Li L, Venkatesan S, Sethu S, Hirao A, Mak TW, Hande MP, Hakem A, Hakem R. El Ghamrasni S, et al. Among authors: hakem a, hakem r. PLoS Genet. 2011 May;7(5):e1001385. doi: 10.1371/journal.pgen.1001385. Epub 2011 May 19. PLoS Genet. 2011. PMID: 21625617 Free PMC article.
Role of Pirh2 in mediating the regulation of p53 and c-Myc.
Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, Madore J, Boutros P, Sheng Y, Chesi M, Bergsagel PL, Perez-Ordonez B, Mes-Masson AM, Penn L, Squire J, Chen X, Jurisica I, Arrowsmith C, Sanchez O, Benchimol S, Hakem R. Hakem A, et al. Among authors: hakem r. PLoS Genet. 2011 Nov;7(11):e1002360. doi: 10.1371/journal.pgen.1002360. Epub 2011 Nov 17. PLoS Genet. 2011. PMID: 22125490 Free PMC article.
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.
Bohgaki M, Bohgaki T, El Ghamrasni S, Srikumar T, Maire G, Panier S, Fradet-Turcotte A, Stewart GS, Raught B, Hakem A, Hakem R. Bohgaki M, et al. Among authors: hakem a, hakem r. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):20982-7. doi: 10.1073/pnas.1320302111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324146 Free PMC article.
117 results