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The novel chemical entity YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppressing repair of DNA double-strand breaks and enhancing radiosensitization.
Sekhar KR, Reddy YT, Reddy PN, Crooks PA, Venkateswaran A, McDonald WH, Geng L, Sasi S, Van Der Waal RP, Roti JL, Salleng KJ, Rachakonda G, Freeman ML. Sekhar KR, et al. Among authors: venkateswaran a. Clin Cancer Res. 2011 Oct 15;17(20):6490-9. doi: 10.1158/1078-0432.CCR-11-1054. Epub 2011 Aug 30. Clin Cancer Res. 2011. PMID: 21878537 Free PMC article.
Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.
Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML. Sekhar KR, et al. Among authors: venkateswaran a. Int J Radiat Oncol Biol Phys. 2014 Aug 1;89(5):1106-1114. doi: 10.1016/j.ijrobp.2014.04.012. Epub 2014 Jul 8. Int J Radiat Oncol Biol Phys. 2014. PMID: 25035215 Free PMC article.
Transcriptome dynamics of Deinococcus radiodurans recovering from ionizing radiation.
Liu Y, Zhou J, Omelchenko MV, Beliaev AS, Venkateswaran A, Stair J, Wu L, Thompson DK, Xu D, Rogozin IB, Gaidamakova EK, Zhai M, Makarova KS, Koonin EV, Daly MJ. Liu Y, et al. Among authors: venkateswaran a. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4191-6. doi: 10.1073/pnas.0630387100. Epub 2003 Mar 21. Proc Natl Acad Sci U S A. 2003. PMID: 12651953 Free PMC article.
How radiation kills cells: survival of Deinococcus radiodurans and Shewanella oneidensis under oxidative stress.
Ghosal D, Omelchenko MV, Gaidamakova EK, Matrosova VY, Vasilenko A, Venkateswaran A, Zhai M, Kostandarithes HM, Brim H, Makarova KS, Wackett LP, Fredrickson JK, Daly MJ. Ghosal D, et al. Among authors: venkateswaran a. FEMS Microbiol Rev. 2005 Apr;29(2):361-75. doi: 10.1016/j.femsre.2004.12.007. FEMS Microbiol Rev. 2005. PMID: 15808748 Free article. Review.
Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags.
Lipton MS, Pasa-Tolic' L, Anderson GA, Anderson DJ, Auberry DL, Battista JR, Daly MJ, Fredrickson J, Hixson KK, Kostandarithes H, Masselon C, Markillie LM, Moore RJ, Romine MF, Shen Y, Stritmatter E, Tolic' N, Udseth HR, Venkateswaran A, Wong KK, Zhao R, Smith RD. Lipton MS, et al. Among authors: venkateswaran a. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11049-54. doi: 10.1073/pnas.172170199. Epub 2002 Aug 12. Proc Natl Acad Sci U S A. 2002. PMID: 12177431 Free PMC article.
Accumulation of Mn(II) in Deinococcus radiodurans facilitates gamma-radiation resistance.
Daly MJ, Gaidamakova EK, Matrosova VY, Vasilenko A, Zhai M, Venkateswaran A, Hess M, Omelchenko MV, Kostandarithes HM, Makarova KS, Wackett LP, Fredrickson JK, Ghosal D. Daly MJ, et al. Among authors: venkateswaran a. Science. 2004 Nov 5;306(5698):1025-8. doi: 10.1126/science.1103185. Epub 2004 Sep 30. Science. 2004. PMID: 15459345
154 results