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Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
Werninghaus K, Babiak A, Gross O, Hölscher C, Dietrich H, Agger EM, Mages J, Mocsai A, Schoenen H, Finger K, Nimmerjahn F, Brown GD, Kirschning C, Heit A, Andersen P, Wagner H, Ruland J, Lang R. Werninghaus K, et al. Among authors: nimmerjahn f. J Exp Med. 2009 Jan 16;206(1):89-97. doi: 10.1084/jem.20081445. Epub 2009 Jan 12. J Exp Med. 2009. PMID: 19139169 Free PMC article.
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.
Schoenen H, Bodendorfer B, Hitchens K, Manzanero S, Werninghaus K, Nimmerjahn F, Agger EM, Stenger S, Andersen P, Ruland J, Brown GD, Wells C, Lang R. Schoenen H, et al. Among authors: nimmerjahn f. J Immunol. 2010 Mar 15;184(6):2756-60. doi: 10.4049/jimmunol.0904013. Epub 2010 Feb 17. J Immunol. 2010. PMID: 20164423 Free PMC article.
NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases.
Sehnert B, Burkhardt H, Wessels JT, Schröder A, May MJ, Vestweber D, Zwerina J, Warnatz K, Nimmerjahn F, Schett G, Dübel S, Voll RE. Sehnert B, et al. Among authors: nimmerjahn f. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16556-61. doi: 10.1073/pnas.1218219110. Epub 2013 Sep 23. Proc Natl Acad Sci U S A. 2013. PMID: 24062461 Free PMC article.
227 results