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Page 1
Atu027 prevents pulmonary metastasis in experimental and spontaneous mouse metastasis models.
Santel A, Aleku M, Röder N, Möpert K, Durieux B, Janke O, Keil O, Endruschat J, Dames S, Lange C, Eisermann M, Löffler K, Fechtner M, Fisch G, Vank C, Schaeper U, Giese K, Kaufmann J. Santel A, et al. Among authors: mopert k. Clin Cancer Res. 2010 Nov 15;16(22):5469-80. doi: 10.1158/1078-0432.CCR-10-1994. Epub 2010 Nov 9. Clin Cancer Res. 2010. PMID: 21062934
Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression.
Aleku M, Schulz P, Keil O, Santel A, Schaeper U, Dieckhoff B, Janke O, Endruschat J, Durieux B, Röder N, Löffler K, Lange C, Fechtner M, Möpert K, Fisch G, Dames S, Arnold W, Jochims K, Giese K, Wiedenmann B, Scholz A, Kaufmann J. Aleku M, et al. Among authors: mopert k. Cancer Res. 2008 Dec 1;68(23):9788-98. doi: 10.1158/0008-5472.CAN-08-2428. Cancer Res. 2008. PMID: 19047158
PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.
Leenders F, Möpert K, Schmiedeknecht A, Santel A, Czauderna F, Aleku M, Penschuck S, Dames S, Sternberger M, Röhl T, Wellmann A, Arnold W, Giese K, Kaufmann J, Klippel A. Leenders F, et al. Among authors: mopert k. EMBO J. 2004 Aug 18;23(16):3303-13. doi: 10.1038/sj.emboj.7600345. Epub 2004 Jul 29. EMBO J. 2004. PMID: 15282551 Free PMC article.